Synthesis and crystal structure of N-(5-acetyl-4methylpyrimidin-2-yl)benzenesulfonamide

被引：5

作者：

Mohamed-Ezzat, Reham A. ^{[1
]}

Kariuki, Benson M. ^{[2
]}

Azzam, Rasha A. ^{[3
]}

机构：

[1] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Cairo, Egypt

[2] Cardiff Univ, Sch Chem, Main Bldg,Pk Pl, Cardiff CF10 3AT, Wales

[3] Helwan Univ, Dept Chem, Cairo, Egypt

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2023年 / 79卷

关键词：

synthesis; pyrimidine sulfonamide; crystal structure; X-ray diffraction; ANTICANCER; SULFONAMIDE;

D O I：

10.1107/S2056989023001871

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

N-(5-Acetyl-4-methylpyrimidin- 2-yl)benzenesulfonamide, C13H13N3O3S, was sythesized and characterized by single-crystal X-ray diffraction. In the crystal, Pi-Pi interactions between the phenyl and pyrimidine groups of neighbouring molecules form molecular chains parallel to [010]. Adjacent molecular chains are linked by N-H...N hydrogen-bonding interactions between the pyrimidine and amine groups of neighbouring molecules, resulting in a three-dimensional network.

引用

页码：331 / +

页数：9

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