Pulmonary Artery Embolization in the Management of Hemoptysis Related to Lung Tumors

被引:3
作者
Claudinot, Amandine [1 ]
Douane, Frederic [2 ]
Morla, Olivier [2 ]
Perret, Christophe [2 ]
Neveu, Marine [2 ]
Thouveny, Francine [3 ]
Bouvier, Antoine [3 ]
Hureaux, Jose [3 ]
Le Guen, Arnaud [4 ]
Jouan, Jeremy [4 ]
Heautot, Jean-Francois [5 ]
Larralde, Antoine [5 ]
Cerasuolo, Damiano [6 ]
Bergot, Emmanuel [7 ]
Fohlen, Audrey [1 ,8 ]
Pelage, Jean-Pierre [1 ,8 ]
机构
[1] CHU Caen, Dept Radiol, F-14000 Caen, France
[2] CHU Nantes, Dept Radiol, F-44000 Nantes, France
[3] CHU Angers, Dept Radiol, F-49933 Angers, France
[4] Ctr Hosp Bretagne Atlantique, Dept Radiol, F-56000 Vannes, France
[5] CHU Rennes, Dept Radiol, F-35000 Rennes, France
[6] CHU Caen, Dept Biostat & Clin Res, F-14000 Caen, France
[7] CHU Caen, Dept Pulmonol & Resp Dis, F-14000 Caen, France
[8] Normandy Univ, UNICAEN, CEA, CNRS,ISTCT,CERVOxy, F-14000 Caen, France
关键词
hemoptysis; pulmonary artery; embolization; lung cancer; MULTIDETECTOR ROW CT; BRONCHIAL ARTERY; PSEUDOANEURYSMS; COMPLICATION; DIAGNOSIS;
D O I
10.3390/jpm13111597
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
(1) Background: Bronchial artery embolization has been shown to be effective in the management of neoplastic hemoptysis. However, knowledge of pulmonary artery embolization is lacking. The aim of this study was to evaluate the safety and efficacy of pulmonary artery embolization in patients presenting with hemoptysis related to lung tumors. (2) Methods: This retrospective study reviewed all consecutive patients with cancer and at least one episode of hemoptysis that required pulmonary artery embolization from December 2008 to December 2020. The endpoints of the study were technical success, clinical success, recurrence of hemoptysis and complications. (3) Results: A total of 92 patients were treated with pulmonary artery embolization (63.1 years +/- 9.9; 70 men). Most patients had stage III or IV advanced disease. Pulmonary artery embolization was technically successful in 82 (89%) patients and clinically successful in 77 (84%) patients. Recurrence occurred in 49% of patients. Infectious complications occurred in 15 patients (16%). The 30-day mortality rate was 31%. At 3 years, the survival rate was 3.6%. Tumor size, tumor cavitation and necrosis and pulmonary artery pseudoaneurysm were significantly associated with recurrence and higher mortality. (4) Conclusions: Pulmonary artery embolization is an effective treatment to initially control hemoptysis in patients with lung carcinoma, but the recurrence rate remains high and overall survival remains poor.
引用
收藏
页数:18
相关论文
共 20 条
[1]   Haemoptysis in adults: a 5-year study using the French nationwide hospital administrative database [J].
Abdulmalak, Caroline ;
Cottenet, Jonathan ;
Beltramo, Guillaume ;
Georges, Marjolaine ;
Camus, Philippe ;
Bonniaud, Philippe ;
Quantin, Catherine .
EUROPEAN RESPIRATORY JOURNAL, 2015, 46 (02) :503-511
[2]   Multi-detector row CT of hemoptysis [J].
Bruzzi, John F. ;
Remy-Jardin, Martine ;
Delhaye, Damien ;
Teisseire, Antoine ;
Khalil, Chadi ;
Remy, Jacques .
RADIOGRAPHICS, 2006, 26 (01) :3-U78
[3]   Pulmonary Artery Pseudoaneurysms: Clinical Features and CT FindingsE [J].
Chen, Ying ;
Gilman, Matthew D. ;
Humphrey, Kathryn L. ;
Salazar, Gloria M. ;
Sharma, Amita ;
Muniappan, Ashok ;
Shepard, Jo-Anne O. ;
Wu, Carol C. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2017, 208 (01) :84-91
[4]   Radiological Management of Hemoptysis: A Comprehensive Review of Diagnostic Imaging and Bronchial Arterial Embolization [J].
Chun, Joo-Young ;
Morgan, Robert ;
Belli, Anna-Maria .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2010, 33 (02) :240-250
[5]   Early Prediction of In-Hospital Mortality of Patients with Hemoptysis: An Approach to Defining Severe Hemoptysis [J].
Fartoukh, Muriel ;
Khoshnood, Babak ;
Parrot, Antoine ;
Khalil, Antoine ;
Carette, Marie-France ;
Stoclin, Annabelle ;
Mayaud, Charles ;
Cadranel, Jacques ;
Ancel, Pierre Yves .
RESPIRATION, 2012, 83 (02) :106-114
[6]   LIFE-THREATENING PULMONARY HEMORRHAGE WITH PULMONARY ARTERIOVENOUS-MALFORMATIONS AND HEREDITARY HEMORRHAGIC TELANGIECTASIA [J].
FERENCE, BA ;
SHANNON, TM ;
WHITE, RI ;
ZAWIN, M ;
BURDGE, CM .
CHEST, 1994, 106 (05) :1387-1390
[7]   Results of Bronchial Artery Embolization for the Treatment of Hemoptysis Caused by Neoplasm [J].
Garcia-Olive, Ignasi ;
Sanz-Santos, Jose ;
Centeno, Carmen ;
Andreo, Felipe ;
Munoz-Ferrer, Aida ;
Serra, Pere ;
Sampere, Jaume ;
Maria Michavila, Josep ;
Muchart, Jordi ;
Ruiz Manzano, Juan .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2014, 25 (02) :221-228
[8]   Severe hemoptysis: From diagnosis to embolization [J].
Khalil, A. ;
Fedida, B. ;
Parrot, A. ;
Haddad, S. ;
Fartoukh, M. ;
Carette, M-F .
DIAGNOSTIC AND INTERVENTIONAL IMAGING, 2015, 96 (7-8) :775-788
[9]   Severe hemoptysis of pulmonary arterial origin - Signs and role of multidetector row CT angiography [J].
Khalil, Antoine ;
Parrot, Antoine ;
Nedelcu, Cosmina ;
Fartoukh, Muriel ;
Marsault, Claude ;
Carette, Marie-France .
CHEST, 2008, 133 (01) :212-219
[10]   Outcomes of Pulmonary Artery Embolization and Stent Graft Placement for the Treatment of Hemoptysis Caused by Lung Tumors [J].
Marcelin, Clement ;
Soussan, Jerome ;
Desmots, Florian ;
Gaubert, Jean-Yves ;
Vidal, Vincent ;
Bartoli, Jean Michel ;
Izaaryene, Jean .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2018, 29 (07) :975-980