Nanotechnology as a Promising Approach for Detection, Diagnosis and Treatment of Food Allergens

被引:3
作者
Rai, Mahendra [1 ,2 ]
Ingle, Avinash P. P. [3 ]
Yadav, Alka [1 ]
Golinska, Patrycja [2 ]
Trzcinska-Wencel, Joanna [2 ]
Rathod, Sanjay [4 ]
Bonde, Shital [1 ]
机构
[1] St Gadge Baba Amravati Univ, Dept Biotechnol, Nanobiotechnol Lab, Amravati, Maharashtra, India
[2] Nicolaus Copernicus Univ, Dept Microbiol, Torun, Poland
[3] Dr Panjabrao Deshmukh Krishi Vidyapeeth, Biotechnol Ctr, Dept Agr Bot, Akola, Maharashtra, India
[4] Univ Pittsburgh, Sch Med, Dept Immunol, Pittsburgh, PA USA
关键词
Food allergens; nanoparticles; diagnosis; delivery; treatment; immunotherapy; NOBLE-METAL NANOPARTICLES; REAL-TIME PCR; PEANUT ALLERGEN; SANDWICH ELISA; QUANTUM DOTS; DENDRITIC CELLS; IMMUNOTHERAPY; PROTEIN; GOLD; SENSITIVITY;
D O I
10.2174/1573413718666220426101432
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Food allergy is one of the world's most serious health problems, which needs new and safer approaches to resolve it. The rapid progress of nanotechnology to tackle the problem of food allergen has generated a new hope. Nanoparticles can be used as a unique system to detect allergens. Furthermore, nanotechnology offers allergen-delivery systems based on nanoparticles as potential adjuvants for allergen-specific immunotherapy. In addition, the use of novel adjuvants using nanoparticles provides a harmless and potentially more effective way of treatment for allergic diseases. For therapeutic applications, nanotechnology-based delivery systems provide increased bioavailability and targeted delivery of food allergens. In addition, nano-based allergen-delivery approaches are mainly aimed at devising a novel and promising approach for allergy vaccines. This review discusses the potential role of nanotechnological strategies for detection, drug delivery, and the treatment of allergies.
引用
收藏
页码:90 / 102
页数:13
相关论文
共 104 条
  • [1] Alvarez Pedro A, 2012, J Allergy (Cairo), V2012, P746125, DOI 10.1155/2012/746125
  • [2] New Trends in Food Allergens Detection: Toward Biosensing Strategies
    Alves, Rita C.
    Fatima Barroso, M.
    Begona Gonzalez-Garcia, Maria
    Oliveira, M. Beatriz P. P.
    Delerue-Matos, Cristina
    [J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2016, 56 (14) : 2304 - 2319
  • [3] Detection of Ara h 1 (a major peanut allergen) in food using an electrochemical gold nanoparticle-coated screen-printed immunosensor
    Alves, Rita C.
    Pimentel, Filipa B.
    Nouws, Henri P. A.
    Marques, Raquel C. B.
    Gonzalez-Garcia, Maria Begona
    Oliveira, M. Beatriz P. P.
    Delerue-Matos, Cristina
    [J]. BIOSENSORS & BIOELECTRONICS, 2015, 64 : 19 - 24
  • [5] [Anonymous], 2015, CURR OPIN FOOD SCI, V4, P92, DOI [10.1016/j.cofs.2015.06.003, DOI 10.1016/J.COFS.2015.06.003]
  • [6] A Systematic Review of Food Allergy: Nanobiosensor and Food Allergen Detection
    Aquino, Adriano
    Conte-Junior, Carlos Adam
    [J]. BIOSENSORS-BASEL, 2020, 10 (12):
  • [7] An SPR based sensor for allergens detection
    Ashley, J.
    Piekarska, M.
    Segers, C.
    Trinh, L.
    Rodgers, T.
    Willey, R.
    Tothill, I. E.
    [J]. BIOSENSORS & BIOELECTRONICS, 2017, 88 : 109 - 113
  • [8] Badea M., 2014, SENSING ELECTROANAL, V8, P59
  • [9] Bahadir EB, 2017, NANOTECH AGRIFOOD, V8, P289, DOI 10.1016/B978-0-12-804301-1.00008-4
  • [10] Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy
    Balenga, Nariman Aghaei Bandbon
    Zahedifard, Farnaz
    Weiss, Richard
    Sarbolouki, Mohammad Nabi
    Thalhamer, Joseph
    Rafati, Sima
    [J]. JOURNAL OF BIOTECHNOLOGY, 2006, 124 (03) : 602 - 614