Bilateral Branch Retinal Vein Occlusion after mRNA-SARS-CoV-2 Booster Dose Vaccination

被引:4
作者
Gironi, Matteo [1 ,2 ]
D'Aloisio, Rossella [2 ]
Verdina, Tommaso [1 ]
Shkurko, Benjamin [3 ]
Toto, Lisa [2 ]
Mastropasqua, Rodolfo [2 ]
机构
[1] Univ Modena & Reggio Emilia, Ophthalmol Clin, Azienda Osped Univ Modena, Policlin, I-41125 Modena, Italy
[2] Univ G dAnnunzio, Dept Med & Sci Ageing, Ophthalmol Clin, I-66100 Chieti, Italy
[3] Univ Parma, Dept Med & Surg, Ophthalmol Clin, I-43121 Parma, Italy
关键词
COVID; SARS-CoV-2; retinal vein occlusion; RVO; vaccination; branch retinal vein occlusion;
D O I
10.3390/jcm12041325
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: We report a case of a patient with a bilateral branch retinal vein occlusion (BRVO) 24 h after a booster vaccination with the mRNA-1237 vaccine. Observations: Fluorescein angiography, performed at three weeks follow-up, showed vascular leakage and blockage, corresponding to hemorrhage areas associated with ischemic areas in the macula and along the arcades involved in the occlusion. Conclusions: The patient was scheduled for urgent injections of intravitreal ranibizumab and laser photocoagulation of the ischemic areas. To the best of our knowledge, this is the first case described of concomitant bilateral RVO after COVID-19 vaccination. The rapid onset of the side effects in a patient with multiple risk factors for thrombotic events suggests that vulnerable microvascular conditions require detailed investigations before administration of a COVID-19 vaccine.
引用
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页数:5
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