Bilateral Branch Retinal Vein Occlusion after mRNA-SARS-CoV-2 Booster Dose Vaccination

被引：4

作者：

Gironi, Matteo ^{[1
,2
]}

D'Aloisio, Rossella ^{[2
]}

Verdina, Tommaso ^{[1
]}

Shkurko, Benjamin ^{[3
]}

Toto, Lisa ^{[2
]}

Mastropasqua, Rodolfo ^{[2
]}

机构：

[1] Univ Modena & Reggio Emilia, Ophthalmol Clin, Azienda Osped Univ Modena, Policlin, I-41125 Modena, Italy

[2] Univ G dAnnunzio, Dept Med & Sci Ageing, Ophthalmol Clin, I-66100 Chieti, Italy

[3] Univ Parma, Dept Med & Surg, Ophthalmol Clin, I-43121 Parma, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 04期

关键词：

COVID; SARS-CoV-2; retinal vein occlusion; RVO; vaccination; branch retinal vein occlusion;

D O I：

10.3390/jcm12041325

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: We report a case of a patient with a bilateral branch retinal vein occlusion (BRVO) 24 h after a booster vaccination with the mRNA-1237 vaccine. Observations: Fluorescein angiography, performed at three weeks follow-up, showed vascular leakage and blockage, corresponding to hemorrhage areas associated with ischemic areas in the macula and along the arcades involved in the occlusion. Conclusions: The patient was scheduled for urgent injections of intravitreal ranibizumab and laser photocoagulation of the ischemic areas. To the best of our knowledge, this is the first case described of concomitant bilateral RVO after COVID-19 vaccination. The rapid onset of the side effects in a patient with multiple risk factors for thrombotic events suggests that vulnerable microvascular conditions require detailed investigations before administration of a COVID-19 vaccine.

引用

页数：5

共 8 条

[1] Comparison of adverse drug reactions among four COVID-19 vaccines in Europe using the EudraVigilance database: Thrombosis at unusual sites [J].

Abbattista, Maria ;

Martinelli, Ida ;

Peyvandi, Flora .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2021, 19 (10) :2554-2558

[2] Uveitis and Other Ocular Complications Following COVID-19 Vaccination [J].

Bolletta, Elena ;

Iannetta, Danilo ;

Mastrofilippo, Valentina ;

De Simone, Luca ;

Gozzi, Fabrizio ;

Croci, Stefania ;

Bonacini, Martina ;

Belloni, Lucia ;

Zerbini, Alessandro ;

Adani, Chantal ;

Fontana, Luigi ;

Salvarani, Carlo ;

Cimino, Luca .

JOURNAL OF CLINICAL MEDICINE, 2021, 10 (24)

[3] Systemic diseases associated with various types of retinal vein occlusion [J].

Hayreh, SS ;

Zimmerman, B ;

McCarthy, MJ ;

Podhajsky, P .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 2001, 131 (01) :61-77

[4] Presumed bilateral branch retinal vein occlusions secondary to antiepileptic agents [J].

Hussain, Rumana N. ;

Banerjee, Somnath .

CLINICAL OPHTHALMOLOGY, 2011, 5 :609-611

[5] Combined central retinal artery and vein occlusion shortly after mRNA-SARS-CoV-2 vaccination [J].

Ikegami, Y. ;

Numaga, J. ;

Okano, N. ;

Fukuda, S. ;

Yamamoto, H. ;

Terada, Y. .

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2021, 114 (12) :884-885

[6] Association between homocyst(e)ine levels and risk of vascular events [J].

Kaplan, ED .

DRUGS OF TODAY, 2003, 39 (03) :175-191

[7] Retinal Hemorrhage after SARS-CoV-2 Vaccination [J].

Park, Hyo Song ;

Byun, Yeojue ;

Byeon, Suk Ho ;

Kim, Sung Soo ;

Kim, Yong Joon ;

Lee, Christopher Seungkyu .

JOURNAL OF CLINICAL MEDICINE, 2021, 10 (23)

[8] Retinal Vein Occlusion Following Two Doses of mRNA-1237 (Moderna) Immunization for SARS-Cov-2: A Case Report [J].

Sacconi, Riccardo ;

Simona, Filippo ;

Forte, Paolo ;

Querques, Giuseppe .

OPHTHALMOLOGY AND THERAPY, 2022, 11 (01) :453-458

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