Visible-Light-Mediated Intermolecular [2+2]-Cycloaddition Reaction of 3-Alkylideneindolin-2-one with Alkenes via Triplet Energy Transfer for the Synthesis of 3-Spirocyclobutyl Oxindoles

被引：8
|
作者：
Shi, Shao-Xian [1 ]
Zhang, Huan-Huan [1 ]
Wang, Yi-Lin [1 ]
Jiang, Lin-Hong [1 ]
Xu, Peng-Fei [1 ,2 ]
Luo, Yong-Chun [1 ,2 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, Lanzhou 730000, Peoples R China
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 29期
关键词：
WELWITINDOLINONE;
D O I：
10.1021/acs.orglett.3c01695
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[2 + 2]-Cycloaddition is the most straightforward approachto theconstruction of cyclobutanes. In this paper, the intermolecular [2+ 2]-cycloaddition reaction of 3-alkylideneindolin-2-ones with alkeneswas achieved. This reaction can be used in the synthesis of 3-spirocyclobutyloxindoles, polycyclic oxindoles, and late stage modification of somedrug molecules.
引用
收藏
页码：5426 / 5430
页数：5
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