Nafion-Titanium (IV) Oxide-Graphene Modified Glassy Carbon Electrode (GCE) Based Electrochemical Sensor for the Voltammetric Determination of the β-blocker Bisoprolol Fumarate

被引：2

作者：

Kocak, Berna ^{[1
,2
]}

Ipek, Yeliz ^{[1
,2
]}

机构：

[1] Munzur Univ, Vocat Sch Tunceli, Chem & Chem Proc Technol Dept, Tunceli, Turkey

[2] Munzur Univ, Rare Earth Element Res & Applicat Ctr, Tunceli, Turkey

来源：

ANALYTICAL LETTERS | 2023年 / 56卷 / 10期

关键词：

Bisoprolol fumarate; differential pulse voltammetry (DPV); electrochemical sensor; graphene; titanium (IV) oxide; PASTE ELECTRODE; AMLODIPINE BESYLATE; TIO2; NANOPARTICLES; HPLC METHOD; HYDROCHLOROTHIAZIDE; VALIDATION; ACETAMINOPHEN; FORMULATIONS; NANOSHEETS; DESIGN;

D O I：

10.1080/00032719.2022.2139837

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A Nafion-titanium (IV) oxide-graphene modified glassy carbon electrode (n-TiO2-GR/GCE) was used for the electrochemical determination of bisoprolol fumarate (BF). The modified electrode was prepared by depositing Nafion-titanium (IV) oxide-graphene onto the glassy carbon electrode by simple drop-casting. Differential pulse voltammetry (DPV) and square wave voltammetry (SWV) were used in the electrochemical determination of bisoprolol fumarate. The linear working range of bisoprolol fumarate for n-TiO2-GR/GCE DPV was from 3.0 x 10(-7) to 5.0 x 10(-6 )mol L-1 and the detection limit was 1.01 x 10(-7 )mol L-1. In addition, with this developed method, the determination of bisoprolol fumarate in tablets was successfully performed with a recovery of 98.65%.

引用

页码：1619 / 1631

页数：13

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