Cryptococcus neoformans Infections Differ Among Human Immunodeficiency Virus (HIV)-Seropositive and HIV-Seronegative Individuals: Results From a Nationwide Surveillance Program in France

被引：6

作者：

Paccoud, Olivier ^{[1
]}

Desnos-Ollivier, Marie ^{[2
,44
]}

Cassaing, Sophie ^{[3
]}

Boukris-Sitbon, Karine ^{[2
]}

Alanio, Alexandre ^{[2
,4
]}

Bellanger, Anne-Pauline ^{[5
]}

Bonnal, Christine ^{[6
]}

Bonhomme, Julie ^{[7
]}

Botterel, Francoise ^{[8
]}

Bougnoux, Marie-Elisabeth ^{[9
,10
]}

Brun, Sophie ^{[11
]}

Chouaki, Taieb ^{[12
,13
]}

Cornet, Muriel ^{[14
]}

Dannaoui, Eric ^{[2
]}

Demar, Magalie ^{[15
]}

Desbois-Nogard, Nicole ^{[16
]}

Durieux, Marie-Fleur ^{[17
]}

Favennec, Loic ^{[18
,19
]}

Fekkar, Arnaud ^{[20
,21
]}

Gabriel, Frederic ^{[22
]}

Gangneux, Jean-Pierre ^{[23
,24
]}

Guitard, Juliette ^{[25
]}

Hasseine, Lilia ^{[26
]}

Huguenin, Antoine ^{[27
]}

Le Gal, Solene ^{[28
]}

Letscher-Bru, Valerie ^{[29
]}

Mahinc, Caroline ^{[30
]}

Morio, Florent ^{[31
]}

Nicolas, Muriel ^{[32
]}

Rouges, Celia ^{[33
]}

Cateau, Estelle ^{[34
]}

Persat, Florence ^{[35
,36
]}

Poirier, Philippe ^{[37
]}

Ranque, Stephane ^{[38
]}

Roosen, Gabrielle ^{[39
]}

Roux, Anne-Laure ^{[40
,41
]}

Sasso, Milene ^{[42
,43
]}

Lortholary, Olivier ^{[1
,2
]}

Lanternier, Fanny ^{[1
,2
]}

机构：

[1] Univ Paris Cite, Necker Enfants Malad Univ Hosp, AP HP, Inst Hosp Univ Imagine,Dept Infect Dis & Trop Med, Paris, France

[2] Univ Paris Cite, Inst Pasteur, Natl Reference Ctr Invas Mycoses & Antifungals, Mycol Dept,Mycol Translat Res Grp, Paris, France

[3] Toulouse III Univ, Toulouse Univ Hosp, Dept Parasitol & Mycol, Restore FLAMES, Toulouse, France

[4] Hop St Louis, AP HP, Lab Parasitol Mycol, Paris, France

[5] Ctr Hosp Univ Besancon, Ctr Natl Rech Sci 6249, Unite Mixte Rech Chrono Environm, Lab Parasitol Mycol, Besancon, France

[6] Bichat Claude Bernard Univ Hosp, AP HP, Lab Parasitol Mycol, Paris, France

[7] Unicaen Univ Normandie, Ctr Hosp Univ Caen, Lab Parasitol Mycol, Toxicol Environm,Milieux Aeriens & Canc Aliments B, Caen, France

[8] Univ Paris Est Creteil, AP HP, Dept Agents Infect, Unite Parasitol Mycol,Dynam Res Unit, Paris, France

[9] Hop Necker Enfants Malad, AP HP, Serv Microbiol Clin, Unite Parasitol Mycol, Paris, France

[10] Univ Paris Cite, Inst Pasteur, Inst Natl Rech Agr Alimentat & Environm USC2019, Unite Biol & Pathogen Fong, Paris, France

[11] Avicenne Hosp, AP HP, Parasitol Mycol Dept, Bobigny, France

[12] Ctr Hosp Univ Amiens Picardie, Serv Parasitol Mycol Med, Amiens, France

[13] Univ Lille, Ctr Natl Rech Sci, Unite Glycobiol Struct & Fonct, Unite Mixte Rech 8576,Inserm U1285, Lille, France

[14] Univ Grenoble Alpes, Grenoble Inst Natl Polytech, Ctr Natl Rech Sci, Ctr Hosp Univ Grenoble Alpes,Serv Parasitol Mycol,, Grenoble, France

[15] Ctr Hosp Cayenne Guyane, Lab Hosp Univ Parasitomycol, Cayenne, France

[16] Ctr Hosp Univ Martinique, Lab Parasitol Mycol, Fort De France, Martinique, France

[17] Ctr Hosp Univ Dupuytren, Lab Parasitol Mycol, Limoges, France

[18] Ctr Hosp Univ Rouen, French Natl Cryptosporidiosis Reference Ctr, Lab Parasitol, Rouen, France

[19] Univ Rouen Normandy, Unite Rech Equipe Accueil 7510, Unite Format & Rech St, Rouen, France

[20] Grp Hosp Pitie Salpetriere, AP HP, Parasitol Mycol, Paris, France

[21] Sorbonne Univ, Ctr Immunol & Malad Infect, Ctr Natl Rech Sci, Inserm,Cimi Paris, Paris, France

[22] Ctr Hosp Univ Bordeaux, Lab Parasitol Mycol, Bordeaux, France

[23] Univ Rennes, Ecole Hautes Etud St publ, Inst Rech St Environm & Travail, Ctr Hosp Univ Rennes,UMR S 1085,Inserm, Rennes, France

[24] Rennes Teaching Hosp, European Confederat Med Mycol Excellence Ctr, Ctr Natl Reference Aspergilloses Chron, Lab Parasitol & Med Mycol, Rennes, France

[25] Sorbonne Univ, Hop St Antoine, AP HP, Ctr Rech St Antoine,Inserm,Ctr Rech Sci St Antoine, Paris, France

[26] Ctr Hosp Univ Nice, Hop Archet, Serv Parasitol Mycol, Nice, France

[27] Univ Reims, Ctr Hosp Univ Reims, Lab Parasitol Mycol, ESCAPE EA7510,Pole Biol Pathol, Rue Gen Koening, Reims, France

[28] Univ Angers, Univ Brest, Ctr Hosp Univ Brest, Lab Parasitol Mycol,Infect Resp Fong, Brest, France

[29] Univ Strasbourg, Hop Univ Strasbourg, Inst Parasitol & Pathol Trop, Lab Parasitol & Mycol Med,Dynam Interact Hote Path, Strasbourg, France

[30] Ctr Hosp Univ St Etienne, Serv Parasitol Mycol, St Etienne, France

[31] Nantes Univ, Ctr Hosp Univ Nantes, Serv Parasitol Mycol, Cibles & Medicaments Infect & Immun, Nantes, France

[32] Ctr Hosp Univ Guadeloupe, Lab Parasitol Mycol, Pointe A Pitre, Guadeloupe, France

[33] Ctr Hosp Univ Cochin, AP HP, Lab Parasitol Mycol, Paris, France

[34] Ctr Hosp Univ Poitiers, Ctr Natl Rech Sci, Unite Mixte Rech, Lab Parasitol Mycol,Ecol & Biol Interact, Poitiers, France

[35] Claude Bernard Univ Lyon 1, Ctr lnnovat Cancerol Lyon, Team Inflammat & Immun Resp Epithelium, UR3738, Pierre Benite, France

[36] Hosp Civils Lyon, Croix Rousse Hosp, Inst Infect Agents, Dept Med Mycol & Parasitol, Lyon, France

[37] Univ Clermont Auvergne, Ctr Hosp Univ Clermont Ferrand, Serv Parasitol Mycol, Inserm,3IHP, Clermont Ferrand, France

[38] Aix Marseille Univ, AP HM, Inst Hosp Univ Mediterranee Infect, Inst Rech Dev,Serv Sante Armees Vecteurs Infect Tr, Marseille, France

[39] Ctr Hosp Tourcoing, Serv Microbiol, Tourcoing, France

[40] Univ Paris Saclay, Univ Versailles St Quentin en Yvelines, Lab Infect & Inflammat, Inserm, Montigny Le Bretonneux, France

[41] Hop Ambroise Pare, AP HP, Microbiol Dept, Grp Hosp Univ Paris Saclay, Boulogne Billancourt, France

[42] Ctr Hosp Univ Nimes, Lab Parasitol Mycol, Montpellier, France

[43] Univ Montpellier, Inst Rech Dev, Ctr Natl Rech Sci, MiVEGEC, Montpellier, France

[44] Inst Pasteur, Natl Reference Ctr Invas Mycoses & Antifungals, 25-28 Rue Docteur Roux, F-75724 Paris 15, France

来源：

OPEN FORUM INFECTIOUS DISEASES | 2024年 / 11卷 / 02期

关键词：

cryptococcal meningitis; cryptococcosis; fungemia; human immunodeficiency virus; EPIDEMIOLOGY;

D O I：

10.1093/ofid/ofad658

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Among 1107 cryptococcosis cases from the French surveillance network (2005-2020), the proportion of HIV-seronegative individuals has recently surpassed that of HIV-seropositive individuals. We observed marked differences in patient characteristics, disease presentations, cryptococcal antigen results, infecting species, and mortality according to HIV serostatus. [GRAPHICS] .

引用

页数：6

共 12 条

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