Role of in vivo confocal microscopy in dry eye disease and eye pain

被引:10
作者
Shetty, Rohit [1 ]
Dua, Harminder S. [2 ]
Tong, Louis [3 ]
Kundu, Gairik [1 ]
Khamar, Pooja [1 ]
Gorimanipalli, Bhavya [1 ]
D'Souza, Sharon [1 ,4 ]
机构
[1] Narayana Nethralaya Eye Hosp, Dept Cornea & Refract Surg, Bangalore, Karnataka, India
[2] Univ Nottingham, Queens Med Ctr, Dept Ophthalmol & Visual Sci, Nottingham, England
[3] Duke Natl Univ Singapore, Singapore Eye Res Inst, Singapore Natl Eye Ctr, Eye Acad Clin Program,Cornea & External Eye Dis Se, Singapore, Singapore
[4] Narayana Nethralaya Eye Hosp, Dept Cornea & Refract Surg, Bengaluru 560010, Karnataka, India
关键词
Cornea; eye pain; IVCM; normal and dry eye; CORNEAL THICKNESS MEASUREMENT; NERVE PLEXUS; DENSITY; ENDOTHELIUM; INNERVATION; EPITHELIUM; MORPHOLOGY; DIAGNOSIS; FEATURES;
D O I
10.4103/IJO.IJO_3013_22
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Dry eye disease is known to have a lot of variability in presentation with overlapping subtypes. Understanding the pathology of this condition will guide therapeutic options. In vivo confocal microscopy is a diagnostic and imaging modality that provides high magnification and high-resolution images of all layers of the cornea and ocular surface. Various structures in the cornea and their alterations due to dry eye have been imaged. The impact of the tear film instability, inflammation, and altered homeostasis on the corneal epithelium, nerves, keratocytes, and dendritic cells have been evaluated across different studies. In addition, key features of IVCM in patients with neuropathic pain have been highlighted in this paper.
引用
收藏
页码:1099 / 1104
页数:6
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