Recent Advances in the Chemical Composition and Biological Activities of Propolis

被引：22
作者：
Belmehdia, Omar [1 ]
El Menyiy, Naoual [2 ]
Bouyahya, Abdelhakim [3 ]
El Baaboua, Aicha [1 ]
El Omari, Nasreddine [4 ]
Gallo, Monica [5 ]
Montesano, Domenico [6 ]
Naviglio, Daniele [7 ]
Zengin, Gokhan [8 ]
Senhaji, Nadia Skali [1 ]
Goh, Bey Hing [9 ,10 ]
Abrini, Jamal [1 ]
机构：
[1] Abdelmalek Essaadi Univ, Fac Sci, Dept Biol, Biotechnol & Appl Microbiol Team, Tetouan, Morocco
[2] Natl Agcy Med & Aromat Plants, Lab Pharmacol, Taounate, Morocco
[3] Mohammed V Univ Rabat, Fac Sci, Dept Biol, Lab Human Pathol Biol, Rabat, Morocco
[4] Mohammed V Univ Rabat, Lab Histol Embryol & Cytogenet, Fac Med & Pharm, Rabat, Morocco
[5] Univ Naples Federico II, Dept Mol Med & Med Biotechnol, Naples, Italy
[6] Univ Naples Federico II, Dept Pharm, Naples, Italy
[7] Univ Naples Federico II, Dept Chem Sci, Naples, Italy
[8] Selcuk Univ, Sci Fac, Dept Biol, TR-42130 Konya, Turkey
[9] Monash Univ Malaysia, Sch Pharm, Biofunct Mol Exploratory BMEX Res Grp, Bandar Sunway, Subang Jaya, Malaysia
[10] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou, Peoples R China
来源：
FOOD REVIEWS INTERNATIONAL | 2023年 / 39卷 / 09期
关键词：
Propolis; bioactive compounds; biological activities; toxicity; BRAZILIAN RED PROPOLIS; PROSTATE-CANCER CELLS; IN-VITRO; ANTIBACTERIAL ACTIVITY; STINGLESS BEES; ETHANOLIC EXTRACT; ANTIPROLIFERATIVE ACTIVITY; TURKISH PROPOLIS; GREEN PROPOLIS; IMMUNOMODULATORY ACTIVITY;
D O I：
10.1080/87559129.2022.2089164
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Propolis is a resinous substance from beehive produced by the combination of plants and bee secretions. For a long time, this substance has gotten high attention in traditional and modern medicine. The aim of this review was to discuss the recent advances in the chemical composition and biological activities of propolis. The search for recent publications was based on several databases, such as PubMed, Google Scholar, Science-Direct, and Web of Sciences using relevant keywords. Literature data showed that several new compounds have recently been identified in propolis. The most important biological properties of propolis were discussed in this review, namely antibacterial, antiparasitic, antiviral, antioxidant, antileishmanial, anti-inflammatory, antidiabetic, immunomodulatory, and anticancer. In terms of safety, the data showed low toxicity of propolis even at high doses. Overall, propolis can be considered a promising source of bioactive compounds for drug development.
引用
收藏
页码：6078 / 6128
页数：51
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