Pemetrexed-Induced Pseudocellulitis: A Diagnostic Conundrum

被引：1

作者：

Horton, Luke A. ^{[1
]}

Lyons, Alexis B. ^{[2
]}

Kwa, Michael C. ^{[2
]}

Chaffins, Marsha L. ^{[2
]}

Veenstra, Jesse ^{[2
]}

机构：

[1] Univ Calif Irvine, Dermatol, Irvine, CA USA

[2] Henry Ford Hlth Syst, Dermatol, Detroit, MI 48202 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 01期

关键词：

supportive onco-dermatology; oncodermatology; inpatient dermatology; complex medical dermatology; dermatology; cellulitus; drug reaction; infectious cellulitis; pseudocellulitis; pemetrexed; EUGLYCEMIC DIABETIC-KETOACIDOSIS; SGLT2; INHIBITORS; EDEMA;

D O I：

10.7759/cureus.52114

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pemetrexed, an anti-folate, antineoplastic agent, effectively treats various malignancies such as non-small cell lung cancer (NSCLC) and mesothelioma. Here, we report two cases of recurrent pemetrexed-induced lower extremity erythema and edema, one in a 60-year-old male and the other in a 47-year-old male, who were both treated for recurrent cellulitis on multiple occasions before finally being diagnosed with pemetrexed-induced pseudocellulitis (PIP), a rarely reported adverse effect. This is an important diagnostic pitfall for clinicians to be aware of, as early recognition may minimize patient morbidity and prevent unnecessary hospitalization and antibiotic use for presumed cellulitis.

引用

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