Prevention of food allergy in infancy: the role of maternal interventions and exposures during pregnancy and lactation

被引：13

作者：

Abrams, Elissa M. ^{[1
,2
,8
]}

Shaker, Marcus S. ^{[3
]}

Chan, Edmond S. ^{[2
]}

Brough, Helen A. ^{[4
,5
,6
]}

Greenhawt, Matthew ^{[7
]}

机构：

[1] Univ Manitoba, Dept Pediat, Sect Allergy & Clin Immunol, Winnipeg, MB, Canada

[2] Univ British Columbia, Dept Pediat, Div Allergy & Immunol, Vancouver, BC, Canada

[3] Childrens Hosp Dartmouth Hitchcock, Dartmouth Geisel Sch Med, Dept Pediat, Sect Allergy Asthma & Clin Immunol, Lebanon, NH USA

[4] Kings Coll London, Sch Life Course Sci & Populat Sci, London, England

[5] Kings Coll London, Sch Immunol & Microbial Sci, London, England

[6] Evelina London Childrens Hosp, Guys & St Thomas NHS Fdn Trust, Childrens Allergy Serv, London, England

[7] Univ Colorado, Childrens Hosp Colorado, Sect Allergy & Immunol, Denver Sch Med, Aurora, CO USA

[8] Univ Manitoba, Dept Pediat, Sect Allergy & Clin Immunol, Winnipeg, MB R3E 0Z2, Canada

来源：

LANCET CHILD & ADOLESCENT HEALTH | 2023年 / 7卷 / 05期

关键词：

VITAMIN-D INSUFFICIENCY; PEANUT CONSUMPTION; DOUBLE-BLIND; ATOPIC DISEASE; COWS MILK; RANDOMIZED-TRIAL; EGG CONSUMPTION; BREAST-MILK; RISK; SENSITIZATION;

D O I：

10.1016/S2352-4642(22)00349-2

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

There is increased focus on the role of maternal interventions in the prevention of food allergy in infancy. There is no role for maternal dietary modifications during pregnancy or lactation, such as allergen avoidance, as a means of infant allergy prevention. Although exclusive breastfeeding is the recommended infant nutrition source globally, the effect of breastfeeding on infant allergy prevention remains unclear. There is emerging evidence that irregular cow's milk exposure (ie, infrequent formula supplementation) might increase the risk of cow's milk allergy. Although further studies are required, there is also emerging evidence that maternal peanut ingestion during breastfeeding along with early peanut introduction in infancy might have a preventive role. The effect of maternal dietary supplementation with vitamin D, omega-3, and prebiotics or probiotics remains unclear.

引用

页码：358 / 366

页数：9

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