Locally advanced squamous cervical carcinoma (M0): management and emerging therapeutic options in the precision radiotherapy era

被引：8
作者：
Parisi, S. [1 ]
Sciacca, M. [1 ]
Ferrantelli, G. [1 ]
Chillari, F. [1 ]
Critelli, P. [1 ]
Venuti, V. [1 ]
Lillo, S. [3 ]
Arcieri, M. [2 ]
Martinelli, C. [2 ]
Pontoriero, A. [1 ]
Minutoli, F. [1 ]
Ercoli, A. [2 ]
Pergolizzi, S. [1 ]
机构：
[1] Univ Messina, Dept Biomed Dent Sci & Morphol & Funct Images, Radiat Oncol Unit, Via Consolare Valeria 1, I-98124 Messina, ME, Italy
[2] Univ Hosp G Martino, Dept Human Pathol Adult & Childhood G Baresi, Obstet & Gynecol Unit, Messina, Italy
[3] Natl Ctr Oncol Hadrontherapy CNAO, Clin Dept, Radiat Oncol Unit, Pavia, Italy
来源：
JAPANESE JOURNAL OF RADIOLOGY | 2023年 / 42卷 / 4期
关键词：
Cervical carcinoma; Locally advanced squamous cervical carcinoma; HPV; PET; Chemoradiotherapy; Brachytherapy; Target therapy; Immunotherapy; MODULATED RADIATION-THERAPY; SOCIETY CONSENSUS GUIDELINES; AMERICAN BRACHYTHERAPY; CONCURRENT CHEMORADIOTHERAPY; PELVIC RADIOTHERAPY; CANCER PATIENTS; UTERINE CERVIX; CELL CARCINOMA; TREATMENT TIME; INTRACAVITARY BRACHYTHERAPY;
D O I：
10.1007/s11604-023-01510-2
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Squamous cervical carcinoma (SCC) requires particular attention in diagnostic and clinical management. New diagnostic tools, such as (positron emission tomography-magnetic resonance imaging) PET-MRI, consent to ameliorate clinical staging accuracy. The availability of new technologies in radiation therapy permits to deliver higher dose lowering toxicities. In this clinical scenario, new surgical concepts could aid in general management. Lastly, new targeted therapies and immunotherapy will have more room in this setting. The aim of this narrative review is to focus both on clinical management and new therapies in the precision radiotherapy era.
引用
收藏
页码：354 / 366
页数：13
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