Initial evaluation of accelerator-based neutron source system at the Shonan Kamakura General Hospital

被引：16

作者：

Suzuki, Shunsuke ^{[1
,2
]}

Nitta, Kazunori ^{[1
]}

Yagihashi, Takayuki ^{[1
]}

Eide, Paul ^{[3
]}

Koivunoro, Hanna ^{[3
]}

Sato, Naoki ^{[1
]}

Gotoh, Shinichi ^{[1
]}

Shiba, Shintaro ^{[4
]}

Omura, Motoko ^{[4
]}

Nagata, Hironori ^{[1
]}

Tanaka, Hiroki ^{[5
]}

机构：

[1] Shonan Kamakura Gen Hosp, Dept Med Phys, 1370-1 Okamoto, Kamakura, Kanagawa 2478533, Japan

[2] Kyoto Univ, Kyoto Univ Katsura, Grad Sch Engn, Kyoto Nishikyo Ku, Kyoto 6158246, Japan

[3] Neutron Therapeut Inc, 1 Ind Dr, Danvers, MA 01923 USA

[4] Shonan Kamakura Gen Hosp, Dept Radiat Oncol, 1370-1 Okamoto, Kamakura, Kanagawa 2478533, Japan

[5] Kyoto Univ, Inst Integrated Radiat & Nucl Sci, Particle Radiat Oncol Res Ctr, 2-Asashiro Nishi,Kumatori Cho, Osaka 5900494, Japan

来源：

APPLIED RADIATION AND ISOTOPES | 2023年 / 199卷

关键词：

Boron neutron capture therapy; Accelerator -based neutron source; Cockcroft-walton type electrostatic accelerator; Quality assurance; CAPTURE THERAPY; RECURRENT HEAD; BNCT; FACILITY;

D O I：

10.1016/j.apradiso.2023.110898

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An accelerator-based boron neutron capture therapy (AB-BNCT) system was installed at the Shonan Kamakura General Hospital (SKGH). We confirmed that a stable operation was possible for 1 h at a current of 30 mA. The evaluated thermal neutron flux was 2.8 x 109 cm-2 s- 1 and in good agreement (& PLUSMN;5%) with the calculated values. The daily variation was within & PLUSMN;2%. The ambient dose rate due to residual radioactivity after irradiation was approximately 5 & mu;Sv/h using a lead shutter.

引用

页数：7

共 25 条

[1] BNCT for advanced or recurrent head and neck cancer [J].

Aihara, Teruhito ;

Morita, Norimasa ;

Kamitani, Nobuhiko ;

Kumada, Hiroaki ;

Ono, Koji ;

Hiratsuka, Junichi ;

Harada, Tamotsu .

APPLIED RADIATION AND ISOTOPES, 2014, 88 :12-15

[2] Quality assurance procedures for the neutron beam monitors at the FiR 1 BNCT facility [J].

Auterinen, I ;

Serén, T ;

Kotiluoto, P ;

Uusi-Simola, J ;

Savolainen, S .

APPLIED RADIATION AND ISOTOPES, 2004, 61 (05) :1015-1019

[3] Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer [J].

Barth, Rolf F. ;

Vicente, M. Graca H. ;

Harling, Otto K. ;

Kiger, W. S., III ;

Riley, Kent J. ;

Binns, Peter J. ;

Wagner, Franz M. ;

Suzuki, Minoru ;

Aihara, Teruhito ;

Kato, Itsuro ;

Kawabata, Shinji .

RADIATION ONCOLOGY, 2012, 7

[4]

Daquino GG, 2008, A review of the recommendations for the physical dosimetry of boron neutron capture therapy (BNCT)

[5] Boron Neutron Capture Therapy in the Treatment of Recurrent Laryngeal Cancer [J].

Haapaniemi, Aaro ;

Kankaanranta, Leena ;

Saat, Riste ;

Koivunoro, Hanna ;

Saarilahti, Kauko ;

Makitie, Antti ;

Atula, Timo ;

Joensuu, Heikki .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 95 (01) :404-410

[6] Determining a methodology of dosimetric quality assurance for commercially available accelerator-based boron neutron capture therapy system [J].

Hirose, Katsumi ;

Kato, Takahiro ;

Harada, Takaomi ;

Motoyanagi, Tomoaki ;

Tanaka, Hiroki ;

Takeuchi, Akihiko ;

Kato, Ryohei ;

Komori, Shinya ;

Yamazaki, Yuhei ;

Arai, Kazuhiro ;

Kadoya, Noriyuki ;

Sato, Mariko ;

Takai, Yoshihiro .

JOURNAL OF RADIATION RESEARCH, 2022, 63 (04) :620-635

[7] Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system [J].

Hu, Naonori ;

Tanaka, Hiroki ;

Kakino, Ryo ;

Yoshikawa, Syuushi ;

Miyao, Mamoru ;

Akita, Kazuhiko ;

Isohashi, Kayako ;

Aihara, Teruhito ;

Nihei, Keiji ;

Ono, Koji .

RADIATION ONCOLOGY, 2021, 16 (01)

[8]

International Atomic Energy Agency, 2001, TECDOC SER

[9]

Jarvinen H., 2003, 214250355339C NUCL R

[10] Boron neutron capture therapy of brain tumors: Clinical trials at the Finnish facility using boronophenylalanine [J].

Heikki Joensuu ;

Leena Kankaanranta ;

Tiina Seppälä ;

Iiro Auterinen ;

Merja Kallio ;

Martti Kulvik ;

Juha Laakso ;

Jyrki Vähätalo ;

Mika Kortesniemi ;

Petri Kotiluoto ;

Tom Serén ;

Johanna Karila ;

Antti Brander ;

Eija Järviluoma ;

Päivi Ryynänen ;

Anders Paetau ;

Inkeri Ruokonen ;

Heikki Minn ;

Mikko Tenhunen ;

Juha Jääskeläinen ;

Markus Färkkilä ;

Sauli Savolainen .

Journal of Neuro-Oncology, 2003, 62 (1) :123-134

← 1 2 3 →