Recent progress in rational design of peroxynitrite fluorescent probes and bioapplication

被引：33
作者：
Xiao, Liyan [1 ]
Sun, Xiaoqian [1 ]
Li, Zhuohang [1 ]
Zhang, Yu [1 ]
Zhang, Peng [1 ,2 ]
He, Yongrui [2 ]
Guo, Bingpeng [3 ]
Yang, Fengtang [1 ]
Shu, Wei [1 ]
机构：
[1] Shandong Univ Technol, Sch Life Sci & Med, Zibo 255000, Peoples R China
[2] Weifang Med Univ, Sch Pharm, Weifang 261053, Peoples R China
[3] Qilu Univ Technol, Shandong Acad Sci, Sch Chem & Chem Engn, Jinan 250103, Peoples R China
来源：
DYES AND PIGMENTS | 2023年 / 216卷
关键词：
Fluorescent probe; Peroxynitrite; Luminous mechanism; Bioimaging; AGGREGATION-INDUCED EMISSION; REACTIVE OXYGEN;
D O I：
10.1016/j.dyepig.2023.111385
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Peroxynitrite (ONOO-), a reactive oxygen species, is extensively found in organisms. It is strongly associated with many diseases, serving as a significant role in physiological and pathological processes. As a result, real-time and in situ detecting of ONOO- is important for the in-depth study of its biological functions. In recent years, the fluorescence detection technology has been widely used in the detection of ONOO-. In this review, we sum-marized and classified ONOO- fluorescent probes according to different interaction mechanisms, and we introduced their performance and applications in biological imaging. The specific challenges and future devel-opment prospects of ONOO- fluorescent probes are also concerned here. We expect that this review not only provides a reference for people who are just beginning to learn, but also provides an overall reference idea for developing a new generation of ONOO- fluorescent probes, promoting its widespread application in practice.
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收藏
页数：15
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