Recent progress in rational design of peroxynitrite fluorescent probes and bioapplication

被引：35

作者：

Xiao, Liyan ^{[1
]}

Sun, Xiaoqian ^{[1
]}

Li, Zhuohang ^{[1
]}

Zhang, Yu ^{[1
]}

Zhang, Peng ^{[1
,2
]}

He, Yongrui ^{[2
]}

Guo, Bingpeng ^{[3
]}

Yang, Fengtang ^{[1
]}

Shu, Wei ^{[1
]}

机构：

[1] Shandong Univ Technol, Sch Life Sci & Med, Zibo 255000, Peoples R China

[2] Weifang Med Univ, Sch Pharm, Weifang 261053, Peoples R China

[3] Qilu Univ Technol, Shandong Acad Sci, Sch Chem & Chem Engn, Jinan 250103, Peoples R China

来源：

DYES AND PIGMENTS | 2023年 / 216卷

关键词：

Fluorescent probe; Peroxynitrite; Luminous mechanism; Bioimaging; AGGREGATION-INDUCED EMISSION; REACTIVE OXYGEN;

D O I：

10.1016/j.dyepig.2023.111385

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Peroxynitrite (ONOO-), a reactive oxygen species, is extensively found in organisms. It is strongly associated with many diseases, serving as a significant role in physiological and pathological processes. As a result, real-time and in situ detecting of ONOO- is important for the in-depth study of its biological functions. In recent years, the fluorescence detection technology has been widely used in the detection of ONOO-. In this review, we sum-marized and classified ONOO- fluorescent probes according to different interaction mechanisms, and we introduced their performance and applications in biological imaging. The specific challenges and future devel-opment prospects of ONOO- fluorescent probes are also concerned here. We expect that this review not only provides a reference for people who are just beginning to learn, but also provides an overall reference idea for developing a new generation of ONOO- fluorescent probes, promoting its widespread application in practice.

引用

页数：15

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