18F-Fluciclovine PET Detected Early Tumor Recurrence in Prostatectomy Bed With Low PSA of 0.3 ng/mL But Negative on 18F-PSMA PET Scan

被引:3
|
作者
Nguyen, Trinh T. [1 ]
Bhosale, Priya R. [2 ]
Lu, Yang [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Nucl Med, Div Diagnost Imaging, 1400 Pressler St, Unit1483, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Abdominal Imaging, Div Diagnost Imaging, Houston, TX USA
关键词
PSMA; PET/CT; fluciclovine; MRI; prostate cancer; metastasis; CANCER PATIENTS; RISING PSA;
D O I
10.1097/RLU.0000000000004356
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 58-year-old man with metastatic prostate cancer was treated with prostatectomy, radiation therapy to bone metastasis, and androgen deprivation therapy plus abiraterone. He had posttreatment nadir PSA of 0.1 ng/mL. A follow-up F-18-fluciclovine PET performed with PSA of 0.3 ng/mL showed a focal tracer-avid lesion in the left prostatectomy bed. This lesion was negative on F-18-DCFPyL PET/CT, but with typical MRI features for disease recurrence. Minimal urinary activity of fluciclovine helped detection of local disease recurrence in the prostatectomy bed.
引用
收藏
页码:69 / 70
页数:2
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