Higher CD56 Expression on Multiple Myeloma Cells Increases CD38 Expression, Reduces Intracellular NAD plus Levels, and Enhances the Efficacy of Daratumumab-Based Treatment Strategies

被引：0
|
作者：
Giorgetti, Giulia [1 ,2 ]
Becherini, Pamela [2 ]
Maroto-Martin, Elena [1 ,3 ]
Fenoglio, Daniela [4 ,5 ,6 ]
Soncini, Debora [2 ]
Martinuzzi, Claudia [4 ]
Bruzzone, Santina [7 ]
Benzi, Andrea [7 ]
Nahimana, Aimable [8 ,9 ]
Uras, Chiara Rosa Maria [10 ]
Schavgoulidze, Anais [1 ,11 ]
Fong, Jessica Ng [1 ]
Lemoli, Roberto M. [12 ,13 ]
Munshi, Nikhil C. [1 ,3 ,14 ]
Fulciniti, Mariateresa [1 ,3 ]
Cea, Michele [4 ,12 ]
机构：
[1] Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA
[2] Univ Genoa, Dept Internal Med & Med Specialties DiMI, Clin Hematol, Genoa, Italy
[3] Harvard Med Sch, Boston, MA USA
[4] IRCCS Osped Policlin San Martino, Genoa, Italy
[5] Univ Genoa, Ctr Excellence Biomed Res, Genoa, Italy
[6] Univ Genoa, Dept Internal Med, Genoa, Italy
[7] Univ Genoa, Dept Expt Med DIMES, Genoa, Italy
[8] Lausanne Univ Hosp, Cent Hematol Lab, Dept Med Lab & Pathol, Lausanne, Switzerland
[9] Univ Lausanne, Lausanne, Switzerland
[10] Univ Genoa, Dept Expt Med, Ctr Excellence Biomed Res, Genoa, Italy
[11] Univ Toulouse, INSERM, UMR1037, Toulouse Canc Res Ctr Oncopole, Toulouse, France
[12] Univ Genoa, Clin Hematol, Dept Internal Med DiMI, Genoa, Italy
[13] IRCCS San Martino Hosp, Genoa, Italy
[14] VA Boston Heathcare Syst, Boston, MA USA
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-189439
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：4
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