Ent-kaurane diterpenoids from the Annonaceae family: a review of research progress and call for further research

被引:9
作者
Ibrahim, Traore S. [1 ]
Khongorzul, Purevdulam [1 ]
Muyaba, Moses [2 ]
Alolga, Raphael N. [1 ]
机构
[1] China Pharmaceut Univ, Sch Tradit Chinese Pharm, Dept Pharmacognosy, State Key Lab Nat Med, Nanjing, Peoples R China
[2] Eden Univ, Sch Pharm, Dept Pharmaceut Chem & Pharmacognosy, Lusaka, Zambia
基金
中国国家自然科学基金;
关键词
Annonaceae; ent-kaurane diterpenoid; biosynthesis; biological activity; isolation; KAURENOIC ACID; XYLOPIA-AETHIOPICA; STEM BARK; ENT-KAUR-16-EN-19-OIC ACID; COPAIFERA-LANGSDORFFII; ARALIA-CONTINENTALIS; MEDICINAL-PLANTS; ETHANOL EXTRACT; MURINE MODELS; FRUITS;
D O I
10.3389/fphar.2023.1227574
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The Annonaceae is one of the plant families with members that are credited with numerous pharmacological functions. Among the group of compounds responsible for these bioactivities are the ent-kaurane diterpenoids. The ent-kauranes are a group of 20-Carbon, tetracyclic diterpenoids that are widely distributed in other plant families including the Annonaceae family. This mini-review focuses mainly on the ent-kaurane diterpenoids isolated from the Annonaceae family, delineates the various biological activities of these compounds, and highlights the research gaps that exist for further scientific scrutiny.
引用
收藏
页数:9
相关论文
共 86 条
[1]  
Adosraku R., 2011, INT J PURE APPL CHEM, V6, P13
[2]   Traditional Uses, Phytochemistry and Pharmacological Activities of Annonacae [J].
Al Kazman, Bassam S. M. ;
Harnett, Joanna E. ;
Hanrahan, Jane R. .
MOLECULES, 2022, 27 (11)
[3]   Forced Degradation Studies, Elucidation of Degradation Pathways and Degradation Kinetics of Xylopic Acid via LC and LC-MS/MS Analyses [J].
Alolga, Raphael N. ;
Ayensu, Isaac ;
Sosu, Jerry X. .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 112 (08) :2029-2036
[4]   Pharmacokinetics and in vitro liver microsomal enzyme metabolism of Xylopic acid [J].
Alolga, Raphael N. ;
Wang, Shi-Lei ;
Ayensu, Isaac ;
Nebeolisa, Chiemezie S. .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 224
[5]   Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation [J].
Alolga, Raphael N. ;
Opoku-Damoah, Yaw ;
Alagpulinsa, David A. ;
Huang, Feng-Qing ;
Ma, Gaoxiang ;
Leon, Maria A. S. C. Chavez ;
Kudzai, Chifodya ;
Yin, Xiaojian ;
Ding, Yang .
BIOMATERIALS, 2021, 268
[6]  
Alves A V. F., 2023, INT J PHARMACEUT, V631, P122497, DOI [10.1016/j.ijpharm.2022.122497, DOI 10.1016/J.IJPHARM.2022.122497]
[7]   Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei [J].
Ameyaw, Elvis O. ;
Asmah, Kodwo B. ;
Biney, Robert P. ;
Henneh, Isaac T. ;
Owusu-Agyei, Phyllis ;
Prah, James ;
Forkuo, Arnold D. .
MALARIA JOURNAL, 2018, 17
[8]   Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain [J].
Ameyaw, Elvis O. ;
Woode, Eric ;
Boakye-Gyasi, Eric ;
Abotsi, Wonder K. M. ;
Kyekyeku, James Oppong ;
Adosraku, Reimmel K. .
PHARMACOGNOSY RESEARCH, 2014, 6 (02) :172-179
[9]   Occurrence, biological activities and synthesis of kaurane diterpenes and their glycosides [J].
Anselmo Garcia, Pablo ;
Braga de Oliveira, Alaide ;
Batista, Ronan .
MOLECULES, 2007, 12 (03) :455-483
[10]   THE TAXONOMIC DISTRIBUTION OF SOME DITERPENE HYDROCARBONS [J].
APLIN, RT ;
CAMBIE, RC ;
RUTLEDGE, PS .
PHYTOCHEMISTRY, 1963, 2 (03) :205-214