Ochratoxin A: Overview of Prevention, Removal, and Detoxification Methods

被引：52

作者：

Ding, Lijuan ^{[1
]}

Han, Meihua ^{[1
]}

Wang, Xiangtao ^{[1
]}

Guo, Yifei ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Plant Dev, 151 Malianwa North Rd, Beijing 100193, Peoples R China

来源：

TOXINS | 2023年 / 15卷 / 09期

关键词：

ochratoxin A; detoxification; biological method; degradation; GAMMA-IRRADIATION; BACILLUS-SUBTILIS; AQUEOUS-SOLUTIONS; COLD-PLASMA; IN-VITRO; A LEVELS; REDUCTION; WINE; CONTAMINATION; ADSORPTION;

D O I：

10.3390/toxins15090565

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Ochratoxins are the secondary metabolites of Penicillium and Aspergillus, among which ochratoxin A (OTA) is the most toxic molecule. OTA is widely found in food and agricultural products. Due to its severe nephrotoxicity, immunotoxicity, neurotoxicity, and teratogenic mutagenesis, it is essential to develop effective, economical, and environmentally friendly methods for OTA decontamination and detoxification. This review mainly summarizes the application of technology in OTA prevention, removal, and detoxification from physical, chemical, and biological aspects, depending on the properties of OTA, and describes the advantages and disadvantages of each method from an objective perspective. Overall, biological methods have the greatest potential to degrade OTA. This review provides some ideas for searching for new strains and degrading enzymes.

引用

页数：15

共 112 条

[1] Effective Detoxification of Aflatoxin B1 and Ochratoxin A Using Magnetic Graphene Oxide Nanocomposite: Isotherm and Kinetic Study [J].

Abbasi Pirouz, Atena ;

Selamat, Jinap ;

Sukor, Rashidah ;

Noorahya Jambari, Nuzul .

COATINGS, 2021, 11 (11)

[2] The efficacy of clay bentonite, date pit, and chitosan nanoparticles in the detoxification of aflatoxin M1 and ochratoxin A from milk [J].

Abdelnaby, Amany ;

Abdelaleem, Nabila M. ;

Elshewy, Elham ;

Mansour, Ayman H. ;

Ibrahim, Samar .

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2022, 29 (14) :20305-20317

[3] Biodegradation of Ochratoxin A for Food and Feed Decontamination [J].

Abrunhosa, Luis ;

Paterson, Robert R. M. ;

Venancio, Armando .

TOXINS, 2010, 2 (05) :1078-1099

[4] Potential Control of Mycotoxigenic Fungi and Ochratoxin A in Stored Coffee Using Gaseous Ozone Treatment [J].

Akbar, Asya ;

Medina, Angel ;

Magan, Naresh .

MICROORGANISMS, 2020, 8 (10) :1-16

[5] Bifunctional clay based sorbent for ?Ochratoxin A? removal and wine fining [J].

Alford, Roi ;

Mishael, Yael G. .

FOOD CHEMISTRY, 2023, 416

[6] A simple chemical method reduces ochratoxin A in contaminated cocoa shells [J].

Amezqueta, S. ;

Gonzalez-Penas, E. ;

Lizarraga, T. ;

Murillo-Arbizu, M. ;

De Cerain, A. Lopez .

JOURNAL OF FOOD PROTECTION, 2008, 71 (07) :1422-1426

[7] Ochratoxin A decontamination: A review [J].

Amezqueta, Susana ;

Gonzalez-Penas, Elena ;

Murillo-Arbizu, Maria ;

de Cerain, Adela Lopez .

FOOD CONTROL, 2009, 20 (04) :326-333

[8]

[Anonymous], 2022, Commission Regulation (EC) No 1370/2022 Commission Regulation (EC) No 1370/2022 of 5 August 2022 Amending Regulation (EC) No 1881/2006 as Regards Maximum Levels of Ochratoxin A in Certain Foodstuffs

[9] Sorption of Ochratoxin A from Aqueous Solutions Using β-Cyclodextrin-Polyurethane Polymer [J].

Appell, Michael ;

Jackson, Michael A. .

TOXINS, 2012, 4 (02) :98-109

[10] Retention of ochratoxin A and fumonisin B1 and B2 from beer on solid surfaces:: comparison of efficiency of adsorbents with different origin [J].

Belajova, Elena ;

Rauova, Drahomira ;

Dasko, Lubomir .

EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2007, 224 (03) :301-308

← 1 2 3 4 5 6 7 8 9 10 →