The emerging role of IL-38 in diseases: A comprehensive review

被引:10
作者
Chen, Weijun [1 ,2 ]
Xi, Shuangyun [1 ,2 ]
Ke, Yong [1 ,2 ]
Lei, Yinlei [1 ,2 ]
机构
[1] Zunyi Med Univ, Ctr Forens Expertise, Affiliated Hosp, Zunyi, Guizhou, Peoples R China
[2] Zunyi Med Univ, Sch Stomatol, Zunyi, Guizhou, Peoples R China
关键词
cardiovascular and cerebrovascular diseases; interleukin-38; lung diseases; signal path; viral infectious diseasesautoimmune diseases; INTERLEUKIN-1; FAMILY; PSORIASIS; RECEPTOR; CELLS; IDENTIFICATION; CYTOKINES; MEMBERS;
D O I
10.1002/iid3.991
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Introduction: Interleukin-38 (IL-38) is a new type of anti-inflammatory cytokine, which is mainly expressed in the immunity-related organs and is involved in various diseases including cardiovascular and cerebrovascular diseases, lung diseases, viral infectious diseases and autoimmune diseases.Aim: This review aims to detail the biological function, receptors and signaling of IL-38, which highlights its therapeutic potential in related diseases.Conclusion: This article provides a comprehensive review of the association between interleukin-38 and related diseases, using interleukin-38 as a keyword and searching the relevant literature through Pubmed and Web of science up to July 2023.
引用
收藏
页数:8
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