共 35 条
Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries
被引:7
作者:

Sengupta, Aditya
论文数: 0 引用数: 0
h-index: 0
机构:
Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA
Boston Childrens Hosp, Dept Cardiac Surg, 300 Longwood Ave, Boston, MA 02115 USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Carreon, Chrystalle Katte
论文数: 0 引用数: 0
h-index: 0
机构:
Boston Childrens Hosp, Cardiac Registry, Dept Cardiol, Boston, MA USA
Boston Childrens Hosp, Dept Pathol, Cardiac Registry, Boston, MA USA
Boston Childrens Hosp, Dept Cardiac Surg, Cardiac Registry, Boston, MA USA
Harvard Med Sch, Dept Pathol, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Gauvreau, Kimberlee
论文数: 0 引用数: 0
h-index: 0
机构:
Harvard Sch Publ Hlth, Dept Biostat, Boston, MA USA
Boston Childrens Hosp, Dept Cardiol, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Lee, Ji M.
论文数: 0 引用数: 0
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机构: Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Sanders, Stephen P.
论文数: 0 引用数: 0
h-index: 0
机构:
Boston Childrens Hosp, Cardiac Registry, Dept Cardiol, Boston, MA USA
Boston Childrens Hosp, Dept Pathol, Cardiac Registry, Boston, MA USA
Boston Childrens Hosp, Dept Cardiac Surg, Cardiac Registry, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Colan, Steven D.
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h-index: 0
机构:
Boston Childrens Hosp, Dept Cardiol, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

del Nido, Pedro J.
论文数: 0 引用数: 0
h-index: 0
机构:
Boston Childrens Hosp, Dept Cardiol, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Mayer, John E.
论文数: 0 引用数: 0
h-index: 0
机构:
Harvard Med Sch, Dept Surg, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA

Nathan, Meena
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h-index: 0
机构:
Harvard Med Sch, Dept Surg, Boston, MA USA Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA
机构:
[1] Boston Childrens Hosp, Dept Cardiac Surg, Boston, MA USA
[2] Boston Childrens Hosp, Cardiac Registry, Dept Cardiol, Boston, MA USA
[3] Boston Childrens Hosp, Dept Pathol, Cardiac Registry, Boston, MA USA
[4] Boston Childrens Hosp, Dept Cardiac Surg, Cardiac Registry, Boston, MA USA
[5] Harvard Med Sch, Dept Pathol, Boston, MA USA
[6] Harvard Sch Publ Hlth, Dept Biostat, Boston, MA USA
[7] Boston Childrens Hosp, Dept Cardiol, Boston, MA USA
[8] Harvard Med Sch, Dept Pediat, Boston, MA USA
[9] Harvard Med Sch, Dept Surg, Boston, MA USA
[10] Boston Childrens Hosp, Dept Cardiac Surg, 300 Longwood Ave, Boston, MA 02115 USA
关键词:
aorta;
congenital;
conotruncal;
root;
valve;
SWITCH OPERATION;
RISK-FACTORS;
REGURGITATION;
DILATATION;
D O I:
10.1016/j.jacc.2023.10.023
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
BACKGROUND Neo-aortic root dilatation can lead to significant late morbidity after the arterial switch operation (ASO) for dextro-transposition of the great arteries (d-TGA). OBJECTIVES We sought to examine the growth of the neo-aortic root in d-TGA. METHODS A single -center, retrospective cohort study of patients who underwent the ASO between July 1, 1981 and September 30, 2022 was performed. Morphology was categorized as dextro-transposition of the great arteries with intact ventricular septum (d-TGA-IVS), dextro-transposition of the great arteries with ventricular septal defect (d-TGAVSD), and double-outlet right ventricle-transposition of the great arteries type (DORV-TGA). Echocardiographically determined diameters and derived z scores were measured at the annulus, sinus of Valsalva, and sinotubular junction immediately before the ASO and throughout follow-up. Trends in root dimensions over time were assessed using linear mixed-effects models. The association between intrinsic morphology and the composite of moderate-severe aortic regurgitation (AR) and neo-aortic valve or root intervention was evaluated with univariable and multivariable Cox proportional hazards models. RESULTS Of 1,359 patients who underwent the ASO, 593 (44%), 666 (49%), and 100 (7%) patients had d-TGA-IVS, d-TGA-VSD, and DORV-TGA, respectively. Each patient underwent a median of 5 echocardiograms (Q1 -Q3: 3-10 echocardiograms) over a median follow-up of 8.6 years (range: 0.1-39.3 years). At 30 years, patients with DORV-TGA demonstrated greater annular (P < 0.001), sinus of Valsalva (P = 0.039), and sinotubular junction (P = 0.041) dilatation relative to patients with d-TGA-IVS. On multivariable analysis, intrinsic anatomy, older age at ASO, at least mild AR at baseline, and high -risk root dilatation were associated with moderate-severe AR and neo-aortic valve or root intervention at late follow-up (all P < 0.05). CONCLUSIONS Longitudinal surveillance of the neo-aortic root is warranted long after the ASO. (J Am Coll Cardiol 2024;83:516-527) (c) 2024 by the American College of Cardiology Foundation.
引用
收藏
页码:516 / 527
页数:12
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h-index: 0
机构:
Childrens Hosp New York, New York, NY USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Frommelt, Michele A.
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp Wisconsin, Milwaukee, WI 53201 USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Lytrivi, Irene D.
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h-index: 0
机构:
Childrens Hosp New York, New York, NY USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Mahgerefteh, Joseph
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp Montefiore, New York, NY USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

McCrindle, Brian W.
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h-index: 0
机构:
Hosp Sick Children, Toronto, ON, Canada Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Pignatelli, Ricardo
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h-index: 0
机构:
Texas Childrens Hosp, Houston, TX 77030 USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Prakash, Ashwin
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h-index: 0
机构:
Boston Childrens Hosp, Boston, MA USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Sachdeva, Ritu
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h-index: 0
机构:
Childrens Healthcare Atlanta, Atlanta, GA USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Soslow, Jonathan H.
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机构:
Vanderbilt Univ, Med Ctr, Nashville, TN USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Spurney, Christopher
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h-index: 0
机构:
Childrens Natl Hlth Syst, Washington, DC USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Taylor, Carolyn L.
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机构:
Med Univ South Carolina, Charleston, SC 29425 USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Thankavel, Poonam P.
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h-index: 0
机构:
Univ Texas Southwestern, Dallas, TX USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Thorsson, Thor
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h-index: 0
机构:
CS Mott Childrens Hosp, Ann Arbor, MI USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Tretter, Justin T.
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h-index: 0
机构:
Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Young, Luciana T.
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h-index: 0
机构:
Ann & Robert H Lurie Childrens Hosp Chicago, Chicago, IL 60611 USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA

Minich, L. LuAnn
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机构:
Univ Utah, Salt Lake City, UT USA Stanford Univ, Sch Med, 750 Welch Rd,Suite 325, Palo Alto, CA 94304 USA
[10]
Aortic valve regurgitation after arterial switch operation for transposition of the great arteries -: Incidence, risk factors, and outcome
[J].
Losay, Jean
;
Touchot, Anita
;
Capderou, Andre
;
Piot, Jean-Dominique
;
Belli, Emre
;
Planche, Claude
;
Serraf, Alain
.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,
2006, 47 (10)
:2057-2062

Losay, Jean
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Touchot, Anita
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Capderou, Andre
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Piot, Jean-Dominique
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Belli, Emre
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Planche, Claude
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France

Serraf, Alain
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France Ctr Chirurg Marie Lennelongue, F-92350 Le Plessis Robinson, France