ANTIBACTERIAL ACTIVITY OF SOME PLANTS EXTRACTS AGAINST PROTEUS MIRABILIS BACTERIA

Background: Medicinal plants are being looked at as potential new sources of medicines that could replace antibiotics in the treatment of antibiotic-resistant bacteria. The aim of this study is to measure the effect of plant extracts on Proteus mirabilis growth to determine the antibacterial activity of them . Methods: Experimental, in vitro, of Al-Mustaqabal University Collage, The effects of four plant extracts on Proteus mirabilis were assessed. At a concentration of 10%, the activity was assessed using the well diffusion method. Result: Four aqueous plant extracts were tested for antibacterial activity (Peganum harmala, Piper nigrum, Syzygium aromaticum and Cinnamomum zeylanicum) has been evaluated against Proteus mirabilis (Isolated from urinary tract infection). The concentration was used for each type of extract 10mg\ml. In this concentration, the aqueous extract was effective against Proteus mirabilis with inhibition zones of 18 mm, 15 mm and 14 mm respectively, and extract of Cinnamomum zeylanicum shown no inhibition zone. Conclusion: The aqueous extract of Peganum harmala against Proteus mirabilis, showed the highest inhibition of 18mm with the concentration 10%. Whereas, aqueous extract of Cinnamomum zeylanicum has no antibacterial activity against Proteus mirabilis.