Effects of Dementia on Outcomes after Cervical Spine Injuries in Elderly Patients: Evaluation of 1512 Cases in a Nationwide Multicenter Study in Japan

被引：0

作者：

Yamada, Yohei ^{[1
]}

Yokogawa, Noriaki ^{[1
]}

Kato, Satoshi ^{[1
]}

Sasagawa, Takeshi ^{[1
,2
]}

Tsuchiya, Hiroyuki ^{[1
]}

Nakashima, Hiroaki ^{[3
]}

Segi, Naoki ^{[3
]}

Ito, Sadayuki ^{[3
]}

Funayama, Toru ^{[4
]}

Eto, Fumihiko ^{[5
]}

Yamaji, Akihiro ^{[6
]}

Yamane, Junichi ^{[7
]}

Nori, Satoshi ^{[8
]}

Furuya, Takeo ^{[9
]}

Yunde, Atsushi ^{[9
]}

Nakajima, Hideaki ^{[10
]}

Yamada, Tomohiro ^{[11
,12
]}

Hasegawa, Tomohiko ^{[11
]}

Terashima, Yoshinori ^{[13
,14
]}

Hirota, Ryosuke ^{[13
]}

Suzuki, Hidenori ^{[15
]}

Imajo, Yasuaki ^{[15
]}

Ikegami, Shota ^{[16
]}

Uehara, Masashi ^{[16
]}

Tonomura, Hitoshi ^{[17
]}

Sakata, Munehiro ^{[17
,18
]}

Hashimoto, Ko ^{[19
]}

Onoda, Yoshito ^{[19
]}

Kawaguchi, Kenichi ^{[20
]}

Haruta, Yohei ^{[20
]}

Suzuki, Nobuyuki ^{[21
]}

Kato, Kenji ^{[21
]}

Uei, Hiroshi ^{[22
,23
]}

Sawada, Hirokatsu ^{[23
]}

Nakanishi, Kazuo ^{[24
]}

Misaki, Kosuke ^{[24
]}

Terai, Hidetomi ^{[25
]}

Tamai, Koji ^{[25
]}

Kuroda, Akiyoshi ^{[26
]}

Inoue, Gen ^{[26
]}

Kakutani, Kenichiro ^{[27
]}

Kakiuchi, Yuji ^{[27
]}

Kiyasu, Katsuhito ^{[28
]}

Tominaga, Hiroyuki ^{[29
]}

Tokumoto, Hiroto ^{[29
]}

Iizuka, Yoichi ^{[30
]}

Takasawa, Eiji ^{[30
]}

Akeda, Koji ^{[31
]}

Takegami, Norihiko ^{[31
]}

Funao, Haruki ^{[32
,33
,34
]}

机构：

[1] Kanazawa Univ, Grad Sch Med Sci, Dept Orthoped Surg, Ishikawa 9208641, Japan

[2] Toyama Prefectural Cent Hosp, Dept Orthoped Surg, Toyama 9308550, Japan

[3] Nagoya Univ, Grad Sch Med, Dept Orthoped Surg, Nagoya 4668550, Japan

[4] Univ Tsukuba, Fac Med, Dept Orthoped Surg, Tsukuba, Ibaraki 3058575, Japan

[5] Univ Tsukuba, Grad Sch Comprehens Human Sci, Dept Orthoped Surg, Tsukuba, Ibaraki 3058575, Japan

[6] Ibaraki Seinan Med Ctr Hosp, Dept Orthoped Surg, Tsukuba, Ibaraki 3060433, Japan

[7] Natl Hosp Org Murayama Med Ctr, Dept Orthoped Surg, Tokyo 2080011, Japan

[8] Keio Univ, Dept Orthoped Surg, Sch Med, 35 Shinanomachi, Tokyo 1608582, Japan

[9] Chiba Univ, Grad Sch Med, Dept Orthoped Surg, Chiba 2608670, Japan

[10] Univ Fukui, Fac Med Sci, Dept Orthoped & Rehabil Med, Fukui 9101193, Japan

[11] Hamamatsu Univ, Dept Orthoped Surg, Sch Med, Hamamatsu, Shizuoka 4313192, Japan

[12] Nagoya Kyoritsu Hosp, Dept Orthoped Surg, Nagoya, Aichi 4540933, Japan

[13] Sapporo Med Univ, Dept Orthoped Surg, Sapporo 0608543, Japan

[14] Matsuda Orthoped Mem Hosp, Dept Orthoped Surg, Sapporo 0010018, Japan

[15] Yamaguchi Univ, Dept Orthoped Surg, Grad Sch Med, Yamaguchi 7558505, Japan

[16] Shinshu Univ, Dept Orthoped Surg, Sch Med, Nagano 3908621, Japan

[17] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Orthoped, Kawaramachi Hirokoji, Kyoto 6028566, Japan

[18] Saiseikai Shiga Hosp, Dept Orthoped, Shiga 5203046, Japan

[19] Tohoku Univ, Dept Orthoped Surg, Grad Sch Med, Sendai, Miyagi 9808574, Japan

[20] Kyushu Univ, Grad Sch Med Sci, Dept Orthoped Surg, Fukuoka 8128582, Japan

[21] Nagoya City Univ, Dept Orthoped Surg, Grad Sch Med Sci, Nagoya 4678601, Japan

[22] Nihon Univ Hosp, Dept Orthoped Surg, Tokyo 1018393, Japan

[23] Nihon Univ, Dept Orthoped Surg, Sch Med, Tokyo 1738610, Japan

[24] Kawasaki Med Sch, Dept Orthoped Traumatol & Spine Surg, Okayama 7010192, Japan

[25] Osaka Metropolitan Univ, Dept Orthoped Surg, Grad Sch Med, Osaka 5458585, Japan

[26] Kitasato Univ, Dept Orthoped Surg, Sch Med, 1 15 1, Minato, Kanagawa 2520374, Japan

[27] Kobe Univ, Dept Orthoped Surg, Grad Sch Med, Kobe 6500017, Japan

[28] Kochi Univ, Kochi Med Sch, Dept Orthoped Surg, Nankoku 7838505, Japan

[29] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Orthoped Surg, Kagoshima 8908520, Japan

[30] Gunma Univ, Dept Orthoped Surg, Grad Sch Med, 3 39 22 Showa, Maebashi 3718511, Japan

[31] Mie Univ, Dept Orthoped Surg, Grad Sch Med, Mie 5148507, Japan

[32] Int Univ Hlth & Welf, Sch Med, Dept Orthoped Surg, Chiba 2860124, Japan

[33] Int Univ Hlth, Welf Narita Hosp, Dept Orthoped Surg, Chiba 2860124, Japan

[34] Int Univ Hlth, Welf Mita Hosp, Spinal Cord Ctr, Dept Orthoped Surg & Spine, Tokyo 1088329, Japan

[35] Univ Tokyo Hosp, Dept Orthoped Surg, Tokyo 1138655, Japan

[36] Osaka Univ, Dept Orthoped Surg, Grad Sch Med, Osaka 5650871, Japan

[37] Tokai Univ, Dept Orthoped Surg, Surg Sci, Sch Med, Shibuya, Kanagawa 2591193, Japan

[38] Tokyo Med & Dent Univ, Dept Orthoped Surg, Yushima 1138519, Japan

[39] Univ Yamanashi, Dept Orthoped Surg, Yamanashi 4093898, Japan

[40] Kyoto Univ, Grad Sch Med, Dept Orthoped Surg, Kyoto 6068501, Japan

[41] Univ Toyama, Fac Med, Dept Orthoped Surg, Toyama 9300194, Japan

[42] Oita Univ, Fac Med, Dept Orthoped Surg, Oita 8795593, Japan

[43] Kansai Med Univ Hosp, Dept Orthoped Surg, Osaka 5731191, Japan

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 05期

关键词：

cervical spine injury; older adults; dementia; short- to middle-term outcome; functional prognosis; complications; mortality; propensity score matching; COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; GLOBAL PREVALENCE; HIP FRACTURE; CORD-INJURY; MORTALITY; COMORBIDITY; DYSPHAGIA; FALLS; EPIDEMIOLOGY;

D O I：

10.3390/jcm12051867

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We aimed to retrospectively investigate the demographic characteristics and short-term outcomes of traumatic cervical spine injuries in patients with dementia. We enrolled 1512 patients aged >= 65 years with traumatic cervical injuries registered in a multicenter study database. Patients were divided into two groups according to the presence of dementia, and 95 patients (6.3%) had dementia. Univariate analysis revealed that the dementia group comprised patients who were older and predominantly female and had lower body mass index, higher modified 5-item frailty index (mFI-5), lower pre-injury activities of daily living (ADLs), and a larger number of comorbidities than patients without dementia. Furthermore, 61 patient pairs were selected through propensity score matching with adjustments for age, sex, pre-injury ADLs, American Spinal Injury Association Impairment Scale score at the time of injury, and the administration of surgical treatment. In the univariate analysis of the matched groups, patients with dementia had significantly lower ADLs at 6 months and a higher incidence of dysphagia up to 6 months than patients without dementia. Kaplan-Meier analysis revealed that patients with dementia had a higher mortality than those without dementia until the last follow-up. Dementia was associated with poor ADLs and higher mortality rates after traumatic cervical spine injuries in elderly patients.

引用

页数：12

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