Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

被引：3

作者：

Hall, Nigel J. ^{[1
,2
]}

Sherratt, Frances C. ^{[3
]}

Eaton, Simon ^{[4
]}

Walker, Erin ^{[5
]}

Chorozoglou, Maria ^{[6
]}

Beasant, Lucy ^{[7
]}

Stanton, Michael ^{[2
]}

Corbett, Harriet ^{[8
]}

Rex, Dean ^{[9
]}

Hutchings, Natalie ^{[10
]}

Dixon, Elizabeth ^{[10
]}

Crawley, Esther ^{[7
]}

Blazeby, Jane ^{[11
]}

Young, Bridget ^{[3
]}

Reading, Isabel ^{[12
]}

机构：

[1] Univ Southampton, Univ Surg Unit, Fac Med, Southampton, England

[2] Southampton Childrens Hosp, Dept Paediat Surg & Urol, Southampton, England

[3] Univ Liverpool, Dept Publ Hlth Policy & Syst, Liverpool, England

[4] UCL Great Ormond St Inst Child Hlth, London, England

[5] Great Ormond St Hosp Sick Children, London, England

[6] Univ Southampton, Fac Med, Southampton Hlth Technol Assessment Ctr, Southampton, England

[7] Univ Bristol, Ctr Acad Child Hlth, Bristol Med Sch, Bristol, England

[8] Alder Hey Childrens NHS Fdn Trust, Dept Surg, Liverpool, England

[9] St Georges Univ Hosp NHS Fdn Trust, Paediat Surg, London, England

[10] Univ Southampton, Fac Med, Southampton Clin Trials Unit, Southampton, England

[11] Univ Bristol, Bristol & Weston Biomed Res Ctr, Populat Hlth Sci, Bristol, England

[12] Univ Southampton, Fac Med, Primary Care Populat Sci & Med Educ, Southampton, England

来源：

BMJ PAEDIATRICS OPEN | 2023年 / 7卷 / 01期

关键词：

Gastroenterology;

D O I：

10.1136/bmjpo-2022-001673

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT. Trial registration number is ISRCTN15830435.

引用

页数：3

共 2 条

[1] Efficacy of non-operative management of uncomplicated acute appendicitis: initial experience in a resource-limited setting
Rodriguez, Ana Gabriela Barria
Romero, Emilio
Guillen, Alan
Fabrega, Lorena
Fernandez, Paulette Serrano
BMJ PAEDIATRICS OPEN, 2025, 9 (01)
[2] Appendectomy versus non-operative treatment for acute uncomplicated appendicitis in children: study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial
Hall, Nigel J.
Eaton, Simon
Abbo, Olivier
Arnaud, Alexis P.
Beaudin, Marianne
Brindle, Mary
Butter, Andreana
Davies, Dafydd
Jancelewicz, Tim
Johnson, Kathy
Keijzer, Richard
Lapidus-Krol, Eveline
Offringa, Martin
Piche, Nelson
Rintala, Risto
Skarsgard, Erik
Svensson, Jan F.
Ungar, Wendy J.
Wester, Tomas
Willan, Andrew R.
Zani, Augusto
St Peter, Shawn D.
Pierro, Agostino
BMJ PAEDIATRICS OPEN, 2017, 1 (01)

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