Recent Advances in Aptasensing Strategies for Monitoring Phycotoxins: Promising for Food Safety

被引:10
|
作者
Zahraee, Hamed [1 ,2 ,3 ]
Mehrzad, Atiyeh [4 ,5 ]
Abnous, Khalil [2 ,3 ]
Chen, Chih-Hsin [6 ]
Khoshbin, Zahra [1 ,2 ,3 ]
Verdian, Asma [4 ]
机构
[1] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Targeted Drug Delivery Res Ctr, Mashhad 9177948564, Iran
[2] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Pharmaceut Res Ctr, Mashhad 9177948564, Iran
[3] Mashhad Univ Med Sci, Sch Pharm, Dept Med Chem, Mashhad 9177948564, Iran
[4] Res Inst Food Sci & Technol RIFST, Dept Food Safety & Qual Control, Mashhad 1314983651, Iran
[5] Res Inst Food Sci & Technol RIFST, Dept Food Biotechnol, Mashhad 1314983651, Iran
[6] Tamkang Univ, Dept Chem, New Taipei 25137, Taiwan
来源
BIOSENSORS-BASEL | 2023年 / 13卷 / 01期
关键词
phycotoxin; aptamer; biosensor; nanomaterial; on-site detection; portable; MICROCYSTIN-LR; FLUORESCENT APTASENSOR; SENSITIVE DETECTION; DNA APTAMER; SAXITOXIN; BINDING; SELECTION; AFFINITY; WATER;
D O I
10.3390/bios13010056
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Phycotoxins or marine toxins cause massive harm to humans, livestock, and pets. Current strategies based on ordinary methods are long time-wise and require expert operators, and are not reliable for on-site and real-time use. Therefore, it is urgent to exploit new detection methods for marine toxins with high sensitivity and specificity, low detection limits, convenience, and high efficiency. Conversely, biosensors can distinguish poisons with less response time and higher selectivity than the common strategies. Aptamer-based biosensors (aptasensors) are potent for environmental monitoring, especially for on-site and real-time determination of marine toxins and freshwater microorganisms, and with a degree of superiority over other biosensors, making them worth considering. This article reviews the designed aptasensors based on the different strategies for detecting the various phycotoxins.
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页数:26
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