Impact of Endoscopic Sleeve Gastroplasty in Non-alcoholic Fatty Liver Disease: a Systematic Review and Meta-analysis

被引:9
|
作者
Nunes, Beanie Conceicao Medeiros [1 ]
de Moura, Diogo Turiani Hourneaux [1 ]
Kum, Angelo So Taa [1 ]
de Oliveira, Guilherme Henrique Peixoto [1 ]
Hirsch, Bruno Salomao [1 ]
Ribeiro, Igor Braga [1 ]
Gomes, Igor Logetto Caetite [1 ]
de Oliveira, Claudia Pinto Marques [2 ]
Mahmood, Sultan [3 ]
Bernardo, Wanderley Marques [1 ]
de Moura, Eduardo Guimaraes Hourneaux [1 ]
机构
[1] Univ Sao Paulo, Dept Gastroenterol, Serv Endoscopia Gastrointestinal, Hosp Clin,Fac Med, Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Dept Gastroenterol, Hosp Clin, Fac Med, Ave Dr Eneas de Carvalho Aguiar 225,6o Andar,Bloco, BR-05403010 Sao Paulo, SP, Brazil
[3] Harvard Med Sch, Ctr Adv Endoscopy, Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA USA
关键词
Endoscopic sleeve gastroplasty; ESG; NAFLD; Obesity; Fatty liver disease; Bariatric; AMERICAN ASSOCIATION; MANAGEMENT; DIAGNOSIS;
D O I
10.1007/s11695-023-06747-4
中图分类号
R61 [外科手术学];
学科分类号
摘要
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. Endoscopic sleeve gastroplasty (ESG) has proven to be feasible, safe, and effective in the management of obesity. We performed the first systematic review and meta-analysis evaluating NAFLD and other metabolic parameters 12 months post-ESG. Four observational studies with a total of 175 patients were included. The results showed a significant (p < 0.05) reduction of 4.85 in hepatic steatosis index (95% CI - 6.02, - 3.67), 0.5 in NAFLD fibrosis score (95% CI - 0.80, - 0.19), 6.32 U/l in ALT (95% CI - 9.52, - 3.11), 17.28% in TWL (95% CI - 18.24, - 16.31), 6.31 kg/m(2) in BMI (95% CI - 8.11, - 4.52), 47.97% in EWL (95% CI - 49.10, - 46.84), and 0.51% in HbA1c (95% CI - 0.90, - 0.12). ESG improves liver parameters, provides weight loss, and reduces HbA1c levels in patients suffering from NAFLD.
引用
收藏
页码:2917 / 2926
页数:10
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