CNS-associated macrophages shape the inflammatory response in a mouse model of Parkinson's disease

被引：10
作者：
Frosch, Maximilian [1 ]
Amann, Lukas [1 ]
Prinz, Marco [1 ,2 ,3 ]
机构：
[1] Univ Freiburg, Inst Neuropathol, Fac Med, Freiburg, Germany
[2] Univ Freiburg, Signalling Res Ctr BIOSS, Freiburg, Germany
[3] Univ Freiburg, Signalling Res Ctr CIBSS, Freiburg, Germany
来源：
NATURE COMMUNICATIONS | 2023年 / 14卷 / 01期
关键词：
PERIVASCULAR MACROPHAGES; MICROGLIA;
D O I：
10.1038/s41467-023-39061-9
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In an alpha-synuclein (α-syn) model of Parkinson’s disease (PD), Schonhoff and colleagues have shown that central nervous system (CNS)-associated macrophages (CAMs), but not microglia, potentially orchestrate CD4+ T cell recruitment and mediate an α-syn-induced inflammatory makeup.
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页数：3
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