Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

被引：32

作者：

Carra, Maria Clotilde ^{[1
,2
,3
]}

Range, Helene ^{[4
,5
,6
]}

Caligiuri, Giuseppina ^{[7
,8
,9
]}

Bouchard, Philippe ^{[1
,10
]}

机构：

[1] Univ Paris Cite, UFR Odontol, 5 Rue Garanciere, F-75006 Paris, France

[2] Rothschild Hosp, AP HP, Serv Odontol, Periodontal & Oral Surg Unit, Paris, France

[3] Sorbonne Paris Cite Epidemiol & Stat Res Ctr CRESS, INSERM, Paris, France

[4] Univ Rennes, UFR Odontol, F-35043 Rennes, France

[5] Ctr Hosp Univ Rennes, Serv Odontol, Rennes, France

[6] Univ Rennes, NUMECAN Inst Nutr Metab & Canc, INSERM, INRAE, Rennes, France

[7] Univ Paris Cite, Paris, France

[8] Univ Sorbonne Paris Nord, Lab Vasc Translat Sci LVTS, INSERM, Paris, France

[9] Hop Univ Paris Nord Val de Seine, Assistance Publ Hop Paris AP HP, Dept Cardiol & Physiol, Site Bichat, Paris, France

[10] Univ Paris Cite, URP 2496, Paris, France

来源：

PERIODONTOLOGY 2000 | 2023年

关键词：

cerebrovascular accident; hypertension; inflammation; myocardial infarction; periodontal inflammation; periodontitis; peripheral arterial disease; ACUTE MYOCARDIAL-INFARCTION; PORPHYROMONAS-GINGIVALIS; BLOOD-PRESSURE; VASCULAR EVENTS; RISK-FACTORS; ACCELERATES ATHEROSCLEROSIS; GLOBAL BURDEN; ORAL-HEALTH; ASSOCIATION; HYPERTENSION;

D O I：

10.1111/prd.12528

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. "Cardiovascular Diseases (CVDs)." WHO, February 1, 2017, (cvds)). Cardiovascular diseases are a group of disorders affecting the heart and blood vessels. They encompass a collection of different conditions, among which atherosclerotic cardiovascular disease (ASCVD) is the most prevalent. CVDs caused by atherosclerosis, that is, ASCVD, are particularly fatal: with heart attack and stroke being together the most prevalent cause of death in the world. To reduce the health burden represented by ASCVD, it is urgent to identify the nature of the "residual risk," beyond the established risk factors (e.g., hypertension) and behavioral factors already maximally targeted by drugs and public health campaigns. Remarkably, periodontitis is increasingly recognized as an independent cardiovascular risk factor.

引用

页数：34

共 152 条

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