Recent advances in protein-based nanoparticles and their applications in the delivery of bioactive compounds

被引:13
作者
Saif, Asifa [1 ]
Anjum, Laiba [1 ]
Faisal, Zargham [1 ]
Akram, Noor [2 ]
Shah, Yasir Abbas [3 ]
Irfan, Rushba [4 ]
Saeed, Farhan [3 ]
Afzaal, Muhammad [3 ]
Asif Shah, Mohd [5 ,6 ,7 ,8 ,9 ]
机构
[1] Bahauddin Zakariya Univ Multan, Dept Human Nutr, Multan, Pakistan
[2] Govt Coll Univ Faisalabad, Dept Food & Nutr, Faisalabad, Pakistan
[3] Govt Coll Univ, Dept Food Sci, Faisalabad, Pakistan
[4] Univ Agr Faisalabad, Inst Home Sci, Faisalabad, Pakistan
[5] Kebri Dehar Univ, Kebri Dehar, Ethiopia
[6] Saveetha Inst Med & Tech Sci, Saveetha Med Coll & Hosp, Ctr Global Hlth Res, Chennai, India
[7] INTI Int Univ, Nilai, Malaysia
[8] Islamic Univ, Islamic Univ Ctr Sci Res, Najaf, Iraq
[9] Kebri Dehar Univ, Kebri Dehar 250, Ethiopia
关键词
Proteins nanocarriers; target delivery; bioactive compounds; stability; bioavailability; DRUG-DELIVERY; CONTROLLED-RELEASE; MICROGELS; CANCER; SYSTEMS; NANOMATERIALS; NANOCARRIERS; FABRICATION; HYDROGELS; NANOGELS;
D O I
10.1080/10942912.2023.2261662
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The target delivery of sensitive ingredients is affected by various factors including hostile processing, and environmental and storage conditions. These factors are significant challenges in the target delivery and stability of bioactive compounds. However, protein-based nanocarriers have the potential to address these challenges. Protein nanocomposites are of special interest in bioactive compound delivery due to their inexpensive synthesis, size, nontoxic nature, and quick removal from the human body. They can be prepared using several procedures including protein encapsulation, template-induced method, nano-spray drying, emulsion method, nanoprecipitation nano-spraying, crosslinking, adsorption, and desolation. A wide range of protein-based nanoparticles is being used in the delivery of bioactive components. The current review discusses the type of protein nanocarrier, methods for preparation, characterization, and potential applications.
引用
收藏
页码:2881 / 2895
页数:15
相关论文
共 102 条
  • [51] Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain
    Kreuter, Jorg
    Hekmatara, Telli
    Dreis, Sebastian
    Vogel, Tikva
    Gelperina, Svetlana
    Langer, Klaus
    [J]. JOURNAL OF CONTROLLED RELEASE, 2007, 118 (01) : 54 - 58
  • [52] Chondroitin sulfate conjugation facilitates tumor cell internalization of albumin nanoparticles for brain-targeted delivery of temozolomide via CD44 receptor-mediated targeting
    Kudarha, Ritu R.
    Sawant, Krutika K.
    [J]. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2021, 11 (05) : 1994 - 2008
  • [53] Lysozyme Uptake by Oxidized Starch Polymer Microgels
    Li, Yuan
    de Vries, Renko
    Kleijn, Mieke
    Slaghek, Ted
    Timmermans, Johan
    Stuart, Martien Cohen
    Norde, Willem
    [J]. BIOMACROMOLECULES, 2010, 11 (07) : 1754 - 1762
  • [54] Preparation and Characterization of Oxidized Starch Polymer Microgels for Encapsulation and Controlled Release of Functional Ingredients
    Li, Yuan
    de Vries, Renko
    Slaghek, Ted
    Timmermans, Johan
    Stuart, Martien A. Cohen
    Norde, Willem
    [J]. BIOMACROMOLECULES, 2009, 10 (07) : 1931 - 1938
  • [55] A sensitive magnetic nanoparticle-based immunoassay of phosphorylated acetylcholinesterase using protein cage templated lead phosphate for signal amplification with graphite furnace atomic absorption spectrometry detection
    Liang, Pei
    Kang, Caiyan
    Yang, Enjian
    Ge, Xiaoxiao
    Du, Dan
    Lin, Yuehe
    [J]. ANALYST, 2016, 141 (07) : 2278 - 2283
  • [56] Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy
    Lin, Han
    Chen, Yu
    Shi, Jianlin
    [J]. CHEMICAL SOCIETY REVIEWS, 2018, 47 (06) : 1938 - 1958
  • [57] Transcytosis - An effective targeting strategy that is complementary to "EPR effect" for pancreatic cancer nano drug delivery
    Liu, Xiangsheng
    Jiang, Jinhong
    Meng, Huan
    [J]. THERANOSTICS, 2019, 9 (26): : 8018 - 8025
  • [58] Protein Nanoparticles as Drug Delivery Carriers for Cancer Therapy
    Lohcharoenkal, Warangkana
    Wang, Liying
    Chen, Yi Charlie
    Rojanasakul, Yon
    [J]. BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [59] Protein-nanoparticle interactions
    Lynch, Iseult
    Dawson, Kenneth A.
    [J]. NANO TODAY, 2008, 3 (1-2) : 40 - 47
  • [60] Three-Dimensional Printing of Ceramics through "Carving" a Gel and "Filling in" the Precursor Polymer
    Mahmoudi, Mohammadreza
    Wang, Chao
    Moreno, Salvador
    Burlison, Scott R.
    Alatalo, Diana
    Hassanipour, Fatemeh
    Smith, Samantha E.
    Naraghi, Mohammad
    Minary-Jolandan, Majid
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2020, 12 (28) : 31984 - 31991