Clinical and Radiological Outcomes of Vertebral Artery Dissecting Aneurysms Treated with Endovascular Treatments: A 12-year Single-Center Experience

■ OBJECTIVE: We aimed to compare the clinical and radiological outcomes of vertebral artery dissecting an-eurysms (VADAs) stratified using different endovascular treatment methods.■ METHODS: We retrospectively reviewed 116 patients with VADAs treated at a single tertiary institute between September 2008 and December 2020. We analyzed and compared the clinical and radiological parameters ac-cording to different treatment methods. ■ RESULTS: In total, 127 endovascular procedures were performed in 116 patients. We initially treated 46 patients with parent artery occlusion, 9 with coil embolization without stent, 43 with single stent with or without coil, 16 with multiple stents with or without coils, and 13 with flow-diverting stent. At the last follow-up (mean 37.8 & PLUSMN; 30.9 months), the complete occlusion rate (85.7%) was higher in the multiple-stent group than in the groups that received other reconstructive treatment methods. Moreover, the recurrence (0%) and retreatment (0%) rates were significantly lower in the multiple stent group (P < 0.001). The coil embolization-only group showed the high-est recurrence (n = 5, 62.5%) and incomplete occlusion (n = 1, 12.5%) rates. The single-stent group showed higher recurrence (n = 9, 22.5%) and retreatment (n = 3, 7%) rates. Multivariate logistic regression analyses showed that coil embolization without stent placement (odds ra-tio = 172.76, 95% confidence interval = 6.83e4366.85; P = 0.002) was significantly associated with recurrence. At the last follow-up (mean, 42.1 & PLUSMN; 37.7 months), we achieved favorable clinical outcomes (modified Rankin Scale & POUND;2) in 106 of 127 patients.■ CONCLUSION: When treating VADAs, multiple stent placements may play a key role in achieving favorable long-term radiological outcomes.