Discrepancy Study of the Chemical Constituents of Panax Ginseng from Different Growth Environments with UPLC-MS-Based Metabolomics Strategy

被引：8

作者：

Sun, Yizheng ^{[1
,2
]}

Liu, Xiaoyan ^{[2
]}

Fu, Xiaojie ^{[3
]}

Xu, Wei ^{[2
]}

Guo, Qingmei ^{[1
]}

Zhang, Youbo ^{[2
]}

机构：

[1] Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Peoples R China

[2] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[3] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Key Lab Chem Biol,Minist Educ, Jinan 250012, Peoples R China

来源：

MOLECULES | 2023年 / 28卷 / 07期

基金：

中国国家自然科学基金;

关键词：

P; ginseng; ginsenosides; growth environment; metabolomics; multivariate statistical analysis; UPLC-MS/MS; RED GINSENG; MASS-SPECTROMETRY; GINSENOSIDES; SAPONINS; IDENTIFICATION;

D O I：

10.3390/molecules28072928

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Panax ginseng (P. ginseng), the dried root and rhizome of P. ginseng C. A. Meyer, is widely used in many fields as dietary supplements and medicine. To characterize the chemical constituents in P. ginseng cultivated in different growth environments, a UPLC-TOF-MS method was established for qualitative analysis. Four hundred and eight ginsenosides, including 81 new compounds, were characterized in P. ginseng from different regions. Among the detected compounds, 361 ginsenosides were recognized in P. ginseng cultivated in the region of Monsoon Climate of Medium Latitudes, possessing the largest amount of ginsenosides in all samples. Furthermore, 41 ginsenosides in 12 batches of P. ginsengs were quantified with a UPLC-MRM-MS method, and P. ginsengs from different regions were distinguished via chemometric analysis. This study showed that the different environments have a greater influence on P. ginseng, which laid a foundation for further quality control of the herb.

引用

页数：12

共 34 条

[31] Study on chemical constituents of herbal formula Er Miao Wan and GC-MS based metabolomics approach to evaluate its therapeutic effects on hyperuricemic rats [J].

Huang, Bixia ;

Hui, Xuewen ;

Wang, Jiancheng ;

Li, Ping ;

Chen, Jun .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 1118 :101-108

[32] Qualitative and quantitative analyses of chemical components of Citri Sarcodactylis Fructus from different origins based on UPLC-Q-Exactive Orbitrap-MS and GC-MS [J].

Ning, Jinrong ;

Wang, Kanghui ;

Yang, Wanling ;

Liu, Mengshi ;

Tian, Jingyuan ;

Wei, Minyan ;

Zheng, Guodong .

FOOD SCIENCE & NUTRITION, 2022, 10 (06) :2057-2070

[33] Comparative study on chemical constituents of different medicinal parts of Lonicera japonica Thunb. Based on LC-MS combined with multivariate statistical analysis [J].

Zhang, Xinrui ;

Yu, Xiao ;

Sun, Xiaomei ;

Meng, Xianbo ;

Fan, Jian ;

Zhang, Fang ;

Zhang, Yongqing .

HELIYON, 2024, 10 (12)

[34] Metabonomics study on the hepatoprotective effect mechanism of polysaccharides from different processed products of Angelica sinensis on layer chickens based on UPLC-Q/TOF-MS/MS, multivariate statistical analysis and conjoint analysis [J].

Wu, Fan-lin ;

Hu, Yong-hao ;

Ji, Peng ;

Li, Chen-chen ;

He, Jian .

BIOMEDICAL CHROMATOGRAPHY, 2022, 36 (06)

← 1 2 3 4 →