Discrepancy Study of the Chemical Constituents of Panax Ginseng from Different Growth Environments with UPLC-MS-Based Metabolomics Strategy

被引：8

作者：

Sun, Yizheng ^{[1
,2
]}

Liu, Xiaoyan ^{[2
]}

Fu, Xiaojie ^{[3
]}

Xu, Wei ^{[2
]}

Guo, Qingmei ^{[1
]}

Zhang, Youbo ^{[2
]}

机构：

[1] Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Peoples R China

[2] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[3] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Key Lab Chem Biol,Minist Educ, Jinan 250012, Peoples R China

来源：

MOLECULES | 2023年 / 28卷 / 07期

基金：

中国国家自然科学基金;

关键词：

P; ginseng; ginsenosides; growth environment; metabolomics; multivariate statistical analysis; UPLC-MS/MS; RED GINSENG; MASS-SPECTROMETRY; GINSENOSIDES; SAPONINS; IDENTIFICATION;

D O I：

10.3390/molecules28072928

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Panax ginseng (P. ginseng), the dried root and rhizome of P. ginseng C. A. Meyer, is widely used in many fields as dietary supplements and medicine. To characterize the chemical constituents in P. ginseng cultivated in different growth environments, a UPLC-TOF-MS method was established for qualitative analysis. Four hundred and eight ginsenosides, including 81 new compounds, were characterized in P. ginseng from different regions. Among the detected compounds, 361 ginsenosides were recognized in P. ginseng cultivated in the region of Monsoon Climate of Medium Latitudes, possessing the largest amount of ginsenosides in all samples. Furthermore, 41 ginsenosides in 12 batches of P. ginsengs were quantified with a UPLC-MRM-MS method, and P. ginsengs from different regions were distinguished via chemometric analysis. This study showed that the different environments have a greater influence on P. ginseng, which laid a foundation for further quality control of the herb.

引用

页数：12

共 34 条

[21] Evaluation and Screening of Hypoglycemic Activity of Total Ginsenosides GBE-5 Fraction From Panax Ginseng Berry Based on UHPLC-MS Metabolomics [J].

Wang, Heyu ;

Tong, Yu ;

Wang, Anqi ;

Li, Ying ;

Lu, Bofan ;

Li, Hui ;

Jiao, Lili ;

Wu, Wei .

FRONTIERS IN NUTRITION, 2022, 9

[22] LC-MS based metabolomics study of different parts of myrtle berry from Sardinia (Italy) [J].

D'Urso, Gilda ;

Sarais, Giorgia ;

Lai, Carla ;

Pizza, Cosimo ;

Montoro, Paola .

JOURNAL OF BERRY RESEARCH, 2017, 7 (03) :217-229

[23] Dynamic variations in the chemical constituents of Tiebangchui stir-fried with Zanba by integrating UPLC-Q-TOF-MS based metabolomics and DESI-MSI [J].

Li, Cong-Ying ;

Sha, Meng-Xiang ;

Pei, Zhao-Qing ;

Zhou, Zhen ;

Tang, Ce ;

Liu, Yue ;

Zhang, Yi .

ARABIAN JOURNAL OF CHEMISTRY, 2023, 16 (08)

[24] Study on hepatotoxicity of different dosages of Polygoni multiflori radix praeparata in rats by metabolomics based on UPLC-Q-TOF-MS [J].

Gong, Xiaohong ;

Liu, Meichen ;

Gong, Lihong ;

Li, Yunxia ;

Peng, Cheng .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 175

[25] Identification of Medicinal Compounds of Fagopyri Dibotryis Rhizome from Different Origins and Its Varieties Using UPLC-MS/MS-Based Metabolomics [J].

Zhang, Chengcai ;

Jiang, Yang ;

Liu, Changzheng ;

Shi, Linyuan ;

Li, Jintong ;

Zeng, Yan ;

Guo, Lanping ;

Wang, Sheng .

METABOLITES, 2022, 12 (09)

[26] Comprehensive investigation on non-volatile and volatile compounds in Auricularia auricula from different regions by UPLC-MS/MS-based metabolomics and GC-IMS [J].

Feng, Kewei ;

Zuo, Rui ;

Chu, Tianyu ;

Zhao, Qi ;

Li, Jiaoyang ;

Liu, Lingxiu ;

Sheng, Qinglin ;

Song, Wei ;

Yuan, Yahong ;

Wang, Yuan ;

Yue, Tianli .

LWT-FOOD SCIENCE AND TECHNOLOGY, 2024, 199

[27] Bioactive Metabolites from the Dusty Seeds of Gastrodia elata Bl., Based on Metabolomics and UPLC-Q-TOF-MS Combined with Molecular Network Strategy [J].

Wang, Yanduo ;

Zhong, Liwen ;

Fang, Huiqi ;

Liu, Zhao ;

Wang, Peng ;

Li, Longfei ;

Chen, Lin ;

Ding, Gang .

PLANTS-BASEL, 2025, 14 (06)

[28] Comparisons of phenolic compounds and antioxidant activities during different growth stages in Artemisia gmelinii Weber ex Stechm with UPLC-QTOF/MS based on a metabolomics approach [J].

Oh, Seon Min ;

Kim, Doo-Young ;

Lee, Su-Yeon ;

Song, Ha Eun ;

Kim, In Seon ;

Seo, Woo Duck ;

Lee, Jeong Hoon ;

Oh, Sei-Ryang ;

Lee, Dae Young ;

Ryu, Hyung Won .

INDUSTRIAL CROPS AND PRODUCTS, 2023, 202

[29] UPLC-MS based metabolomics study on Senecio scandens and S. vulgaris: an approach for the differentiation of two Senecio herbs with similar morphology but different toxicity [J].

Aizhen Xiong ;

Li Yang ;

Lili Ji ;

Zaiyong Wang ;

Xuejing Yang ;

Ying Chen ;

Xiuli Wang ;

Changhong Wang ;

Zhengtao Wang .

Metabolomics, 2012, 8 :614-623

[30] UPLC-Q TOF-MS-Based metabolomics and anti-myocardial ischemia activity of Dioscoreae Nipponicae Rhizoma from different geographical origins [J].

Yang, Xiao-fang ;

Miao, Yu ;

Yang, Da-wei ;

Kong, Ren ;

Yuan, Bo ;

Quan, Jian-ye ;

Bu, Wei .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 234

← 1 2 3 4 →