Investigation of the monocyte/high-density lipoprotein ratio as a prognostic criterion in burn patients

被引:0
作者
Akkoc, Mehmet Fatih [1 ]
Bulbuloglu, Semra [2 ,4 ]
Kapi, Emin [3 ]
Bayram, Mehmet [1 ]
Gurgah, Tuba [1 ]
机构
[1] Dicle Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, Diyarbakir, Turkiye
[2] Istanbul Aydin Univ, Fac Hlth Sci, Nursing Dept, Div Surg Nursing, Istanbul, Turkiye
[3] Univ Hlth Sci, Fac Med, Adana Hlth Applicat & Res Ctr, Dept Plast Reconstruct & Aesthet Surg, Adana, Turkiye
[4] Istanbul Aydin Univ, Fac Hlth Sci, Nursing Dept, Div Surg Nursing, Florya Campus, Istanbul, Turkiye
关键词
burn injuries; C-reactive protein; high-density lipoprotein; monocyte; INFLAMMATORY RESPONSE; ORGAN DYSFUNCTION; RISK-FACTORS; SEPSIS;
D O I
10.1111/wrr.13070
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In this study, it was aimed to investigate the monocyte/high-density lipoprotein ratio as a prognostic criterion in adult burn patients. A descriptive and cross-sectional method was adopted in this study. The sample included 177 patients with burn injuries. This study was conducted in a research and training hospital in Turkey. Data were collected by the researchers in the burn unit. Descriptive methods, Kruskal-Wallis, Mann- Whitney U, ROC curve, and correlation analyses were used for the statistical analyses of the data. While 66.1% of the patients were second-degree burn patients, 96.6% of all patients recovered and were discharged from the hospital, and the rest died. In this study, the monocyte/high-density lipoprotein ratios of the patients decreased as their clinical condition worsened. The mean C-reactive protein value of the patients was 8.52 +/- 5.02 on the 7th day. A statistically significant correlation was found between an increase in monocyte counts and a decrease in high-density lipoprotein concentrations at the 24th hour, 3rd day and 7th day after the burn (p < 0.01). The monocyte/highdensity lipoprotein ratio can be considered a biomarker in the identification and followup of sepsis and morbidity durations in burn patients. A low monocyte/high-density lipoprotein ratio in burn patients can provide an insight into the severity of sepsis.
引用
收藏
页码:233 / 239
页数:7
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