Acral Melanoma: Clinical Advances and Hope for the Future

被引：0

作者：

Perez, Matthew C. ^{[1
]}

Messina, Jane L. ^{[1
,2
]}

Karapetyan, Lilit ^{[1
]}

Neves, Rogerio I. ^{[1
,3
]}

Sondak, Vernon K. ^{[1
,4
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Cutaneous Oncol, Tampa, FL USA

[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Anat Pathol, Tampa, FL USA

[3] H Lee Moffitt Canc Ctr & Res Inst, Program Plast Surg & Reconstruct Oncol, Tampa, FL USA

[4] Dept Cutaneous Oncol, 10920 N McKinley Dr, Tampa, FL 33612 USA

来源：

CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY | 2023年 / 21卷 / 08期

关键词：

Acral lentiginous melanoma; acral melanoma; cutaneous melanoma; LENTIGINOUS MELANOMA; CUTANEOUS MELANOMA; METASTATIC MELANOMA; MALIGNANT-MELANOMA; EXCISION MARGINS; SURGICAL MARGINS; BRAF INHIBITORS; CTLA-4; BLOCKADE; UNITED-STATES; SINGLE-ARM;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Acral melanoma is a rare subtype of melanoma with unique histologic and biologic characteristics. Given its relative rarity compared with nonacral cutaneous melanoma, acral melanoma has been understudied and underrepresented in modern-day prospective clinical trials that have shaped the contemporary management of advanced cutaneous melanoma. Therefore, treatment principles for advanced acral melanoma are mostly derived from retrospective anal-yses or extrapolated from data largely based on nonacral cutaneous melanoma. Further studies are warranted to evaluate the efficacy of systemic immune and targeted molecular therapies, and to identify molecular targets for patients with advanced acral melanoma.

引用

页码：400 / 409

页数：10

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