Electrochemical Detection of Hydrogen Peroxide Using Copper-Based Metal-Organic Frameworks: Nanoarchitectonics and Sensing Performance

Cu-MOFs are exciting materials with lots of unique characteristics which will be suitable for sensing applications. To date, there have not been any published review on the suitability and efficiency of Cu-MOFs on hydrogen peroxide sensing, despite its huge potential in this regard. This systematic review assessed published articles on the subject using the Web of Science. The included studies were assessed in terms of quality using the risk of bias assessment criteria. Out of the 101 screened articles, 50 studies were eligible and included in this review. Non-enzymatic detection of hydrogen peroxide using copper-based MOFs exhibited better performance in terms of limit of detection, sensitivity, and linear response than enzyme-assisted detection. Ligand type and Cu-MOF synthetic techniques demonstrated a great effect on the structural property of the synthesized MOF, which in turn improved its catalytic property. Based on the available data in the reviewed articles. Cu-MOFs has great potential for use as commercial hydrogen peroxide sensor. The successful design of a sensitive, accurate, and stable hydrogen peroxide sensor will be a significant breakthrough for industrial, medical, and environmental applications.