Are Tp-e interval and QT dispersion values important in children with coeliac disease?

被引:1
作者
Birinci, Hakan [1 ]
Yolcu, Canan [2 ]
Dogan, Guzide [3 ]
Basaran, Meryem K. [4 ]
Elevli, Murat [1 ]
机构
[1] Hlth Sci Univ, Haseki Training & Res Hosp, Dept Pediat, Istanbul, Turkey
[2] Hlth Sci Univ, Haseki Training & Res Hosp, Dept Pediat Cardiol, Istanbul, Turkey
[3] Bezmialem Vakif Univ, Dept Pediat Gastroentrol Hepatol & Nutr, Istanbul, Turkey
[4] Gaziosmanpasa Training & Res Hosp, Dept Pediat Gastroentrol Hepatol & Nutr, Istanbul, Turkey
关键词
Child; Coeliac disease; QT dispersion; repolarisation; Tp-e; VENTRICULAR-ARRHYTHMIAS; E/QT RATIO; PREVALENCE; RISK; WAVE;
D O I
10.1017/S1047951122003213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: Coeliac disease is an autoimmune intestinal disease that develops with permanent intolerance to gluten and similar cereal proteins. It can damage to many tissues, including myocardium, by autoimmune mechanisms. In our study, we aimed to investigate the effect of coeliac disease on cardiac electrical activity by comparing the Tp-e interval and Qt dispersion values of coeliac patients with healthy children. Methods: Fifty-seven coeliac patients and 57 healthy children were included in the study. Sociodemographic findings, physical examinations, symptoms, laboratory values, dietary compliance, endoscopy, and pathological findings were recorded into a standardised form. Electrocardiogram parameters were calculated, and echocardiography findings were noted. Results: No statistically significant difference was found between the two groups in terms of age, gender, heart rate, electrocardiogram parameters such as p wave, PR interval, QRS complex, QT interval, and QTc values. Tp-e interval, Tp-e / QT ratio, and Tp-e / QTc ratio were statistically significantly higher in the patient group compared to the control group. Ejection fraction and fractional shortening values were significantly lower in the patient group compared to the control group. In the patient group, Tp-e interval, Tp-e / QT ratio, Tp-e / QTc ratio, and QTc dispersion were statistically significantly higher in patients with tissue transglutaminase IgA positive compared to patients with tissue transglutaminase IgA negative. Conclusion: Our study gives important findings in terms of detecting early signs of future cardiovascular events in childhood age group coeliac patients.
引用
收藏
页码:1853 / 1858
页数:6
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