Stimuli-triggered Self-Assembly of Gold Nanoparticles: Recent Advances in Fabrication and Biomedical Applications

被引:0
|
作者
Zhao, Yan [1 ,2 ,3 ]
Cui, Chaoxiang [1 ,2 ,4 ]
Fan, Guohua [4 ]
Shi, Haibin [1 ,2 ]
机构
[1] Soochow Univ, Sch Radiat Med & Protect, State Key Lab Radiat Med & Protect, Suzhou 215123, Peoples R China
[2] Soochow Univ, Collaborat Innovat Ctr Radiol Med Jiangsu Higher E, Suzhou 215123, Peoples R China
[3] Shanghai Jiao Tong Univ, Suzhou Kowloon Hosp, Sch Med, Dept Radiol, Suzhou 215028, Peoples R China
[4] Soochow Univ, Affiliated Hosp 2, Dept Radiol, Suzhou 215004, Peoples R China
基金
中国国家自然科学基金;
关键词
gold nanoparticles; self-assembly; stimuli-responsive; molecular imaging; tumor theranostics; AGGREGATION; SURFACE; TUMORS; SIZE; UV; MICROENVIRONMENT; PERFORMANCE; RETENTION; DRIVEN; ASSAY;
D O I
10.1002/asia.202400015
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Gold nanoparticles have been widely used in engineering, material chemistry, and biomedical applications owing to their ease of synthesis and functionalization, localized surface plasmon resonance (LSPR), great chemical stability, excellent biocompatibility, tunable optical and electronic property. In recent years, the decoration and modification of gold nanoparticles with small molecules, ligands, surfactants, peptides, DNA/RNA, and proteins have been systematically studied. In this review, we summarize the recent approaches on stimuli-triggered self-assembly of gold nanoparticles and introduce the breakthrough of gold nanoparticles in disease diagnosis and treatment. Finally, we discuss the current challenge and future prospective of stimuli-responsive gold nanoparticles for biomedical applications. This review summarizes recent progress in the development of stimuli-triggered self-assembly on gold nanoparticles and introduce the breakthrough of gold nanoparticles in disease diagnosis and treatment. In addition, the current challenge and future prospective of stimuli-responsive gold nanoparticles for biomedical applications are discussed. image
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页数:12
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