Value of [18F]FDG PET/CT in Diagnosis and Management of Spondylodiscitis

Vertebral osteomyelitis is the third most common form of osteomyelitis in patients over 50 years of age. Whereas prompt (pathogen-directed) therapy is crucially associated with better outcomes, the heterogeneous clinical presentation of disease with unspecific symptoms often delays adequate treatment initiation. Diagnosis requires a careful investigation of medical history, clinical findings and diagnostic imaging, including magnetic resonance imaging and nuclear medicine techniques. Due to its high sensitivity, [F-18]FDG PET/CT is becoming increasingly important in diagnosis and management of spondylodiscitis, especially in the postoperative setting with presence of spinal hardware or other implantable devices in which MRI is limited.