Moonlighting Proteins: Diverse Functions Found in Fungi

被引:4
作者
Curtis, Nicole J. [1 ]
Patel, Krupa J. [1 ]
Rizwan, Amina [2 ]
Jeffery, Constance J. [1 ]
机构
[1] Univ Illinois, Dept Biol Sci, Chicago, IL 60607 USA
[2] Bay Path Univ, Longmeadow, MA 01106 USA
关键词
moonlighting protein; multifunctional; RNA binding proteins; multiprotein complex; enzymes; transcription factor; GROUP-I INTRON; CANDIDA-ALBICANS; SACCHAROMYCES-CEREVISIAE; RNA-BINDING; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; PARACOCCIDIOIDES-BRASILIENSIS; MESSENGER-RNA; CELL-WALL; PYRUVATE-CARBOXYLASE; HUMAN PLASMINOGEN;
D O I
10.3390/jof9111107
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Moonlighting proteins combine multiple functions in one polypeptide chain. An increasing number of moonlighting proteins are being found in diverse fungal taxa that vary in morphology, life cycle, and ecological niche. In this mini-review we discuss examples of moonlighting proteins in fungi that illustrate their roles in transcription and DNA metabolism, translation and RNA metabolism, protein folding, and regulation of protein function, and their interaction with other cell types and host proteins.
引用
收藏
页数:14
相关论文
共 99 条
  • [1] The glucose-regulated nuclear localization of hexokinase 2 in Saccharomyces cerevisiae is Mig1-dependent
    Ahuatzi, D
    Herrero, P
    de la Cera, T
    Moreno, F
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (14) : 14440 - 14446
  • [2] Physical Features of Intracellular Proteins that Moonlight on the Cell Surface
    Amblee, Vaishak
    Jeffery, Constance J.
    [J]. PLOS ONE, 2015, 10 (06):
  • [3] Moonlighting proteins in medically relevant fungi
    Arvizu-Rubio, Verania J.
    Garcia-Carnero, Laura C.
    Manuel Mora-Montes, Hector
    [J]. PEERJ, 2022, 10
  • [4] Targeted mRNA degradation by deadenylation-independent decapping
    Badis, G
    Saveanu, C
    Fromont-Racine, M
    Jacquier, A
    [J]. MOLECULAR CELL, 2004, 15 (01) : 5 - 15
  • [5] The yeast prion protein Ure2 shows glutathione peroxidase activity in both native and fibrillar forms
    Bai, M
    Zhou, JM
    Perrett, S
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (48) : 50025 - 50030
  • [6] Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells
    Barbosa, MS
    Báo, SN
    Andreotti, PF
    de Faria, FP
    Felipe, MSS
    Feitosa, LD
    Mendes-Giannini, MJS
    Soares, CMD
    [J]. INFECTION AND IMMUNITY, 2006, 74 (01) : 382 - 389
  • [7] Bateman JM, 2002, GENETICS, V161, P1043
  • [8] INDICATION OF A SPECIFIC REGULATORY BINDING PROTEIN FOR ORNITHINETRANSCARBAMYLASE IN SACCHAROMYCES CEREVISIAE
    BECHET, J
    WIAME, JM
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1965, 21 (03) : 226 - &
  • [9] The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs
    Beckmann, Benedikt M.
    Horos, Rastislav
    Fischer, Bernd
    Castello, Alfredo
    Eichelbaum, Katrin
    Alleaume, Anne-Marie
    Schwarzl, Thomas
    Curk, Tomaz
    Foehr, Sophia
    Huber, Wolfgang
    Krijgsveld, Jeroen
    Hentze, Matthias W.
    [J]. NATURE COMMUNICATIONS, 2015, 6
  • [10] INHIBITION OF 6-PHOSPHOGLUCONATE DEHYDROGENASE (DECARBOXYLATING) BY GLUCOSE 1,6-BISPHOSPHATE
    BEITNER, R
    NORDENBERG, J
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 583 (02) : 266 - 269