Use of biologics for the management of Crohn's disease: IG-IBD technical review based on the GRADE methodology

被引：2

作者：

Bonovas, Stefanos ^{[1
,2
]}

Piovani, Daniele ^{[1
,2
]}

Pansieri, Claudia ^{[1
,2
]}

Macaluso, Fabio Salvatore ^{[3
]}

Orlando, Ambrogio ^{[3
]}

Festa, Stefano ^{[4
]}

Papi, Claudio ^{[4
]}

Pugliese, Daniela ^{[5
]}

Armuzzi, Alessandro ^{[1
,6
]}

机构：

[1] Humanitas Univ, Dept Biomed Sci, Via R Levi Montalcini 4, I-20072 Milan, Italy

[2] IRCCS Humanitas Res Hosp, Milan, Italy

[3] Villa Sofia Cervello Hosp, IBD Unit, Palermo, Italy

[4] San Filippo Neri Hosp, IBD Unit, Rome, Italy

[5] Policlin Univ A Gemelli IRCCS Fdn, Dept Med & Surg Sci, Div Internal Med & Gastroenterol, Rome, Italy

[6] IRCCS Humanitas Res Hosp, IBD Ctr, Milan, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2023年 / 55卷 / 06期

关键词：

Crohn's disease; Guidelines; GRADE; MAINTENANCE THERAPY; INFLIXIMAB MAINTENANCE; JAPANESE PATIENTS; ADALIMUMAB; INDUCTION; METAANALYSIS; USTEKINUMAB; VEDOLIZUMAB; REMISSION; AZATHIOPRINE;

D O I：

10.1016/j.dld.2023.02.019

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The therapeutic armamentarium for the management of Crohn's disease (CD) is rapidly expanding. Sev-eral biologic therapies (e.g. infliximab, adalimumab, vedolizumab, and ustekinumab) have been regulatory approved, and there is considerable practice variability in the treatment of patients with CD. This technical review systematically searched and identified the current evidence, synthesized it using meta-analytic methodology, appraised its quality, and concisely presented it, thus forming the basis for developing clinical practice recommendations on the use of biologic treatments in adult patients with CD. (c) 2023 The Author(s). Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.

引用

页码：695 / 703

页数：9

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