Recent advances in oxidative phenol coupling for the total synthesis of natural products

被引:22
|
作者
Carson, Matthew C. [1 ]
Kozlowski, Marisa C. [1 ]
机构
[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, Philadelphia, PA 19104 USA
关键词
BOND-FORMING REACTIONS; ENANTIOSELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITIES; EFFICIENT SYNTHESIS; FORMAL SYNTHESIS; CELL-DIVISION; USNIC ACID; HONOKIOL; BIOSYNTHESIS; DERIVATIVES;
D O I
10.1039/d3np00009e
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Covering: 2008 to 2023 This review will describe oxidative phenol coupling as applied in the total synthesis of natural products. This review covers catalytic and electrochemical methods with a brief comparison to stoichiometric and enzymatic systems assessing their practicality, atom economy, and other measures. Natural products forged by C-C and C-O oxidative phenol couplings as well as from alkenyl phenol couplings will be addressed. Additionally, exploration into catalytic oxidative coupling of phenols and other related species (carbazoles, indoles, aryl ethers, etc.) will be surveyed. Future directions of this particular area of research will also be assessed.
引用
收藏
页码:208 / 227
页数:20
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