Gut microbiota and neonatal acute kidney injury biomarkers

被引:4
作者
Yang, Kun [1 ,2 ,3 ]
Du, Guoxia [1 ,2 ,3 ]
Liu, Jinjing [1 ,2 ,3 ]
Zhao, Shuai [1 ,2 ,3 ]
Dong, Wenbin [1 ,2 ,3 ]
机构
[1] Southwest Med Univ, Dept Pediat, Div Neonatol, Affiliated Hosp, Luzhou 646000, Peoples R China
[2] Southwest Med Univ, Dept Perinatol, Affiliated Hosp, Luzhou 646000, Peoples R China
[3] Sichuan Clin Res Ctr Birth Defects, Luzhou 646000, Peoples R China
基金
中国国家自然科学基金;
关键词
Gut microbiota; Neonatal; Acute kidney injury; Biomarkers; Gut-kidney axis; GELATINASE-ASSOCIATED LIPOCALIN; TRIMETHYLAMINE N-OXIDE; CHAIN FATTY-ACID; SERUM CYSTATIN C; URINE BIOMARKERS; CARDIOPULMONARY BYPASS; ISCHEMIA-REPERFUSION; PHOSPHORUS DIET; PROTECTS; SEPSIS;
D O I
10.1007/s00467-023-05931-z
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
One of the most frequent issues in newborns is acute kidney injury (AKI), which can lengthen their hospital stay or potentially raise their chance of dying. The gut-kidney axis establishes a bidirectional interplay between gut microbiota and kidney illness, particularly AKI, and demonstrates the importance of gut microbiota to host health. Since the ability to predict neonatal AKI using blood creatinine and urine output as evaluation parameters is somewhat constrained, a number of interesting biomarkers have been developed. There are few in-depth studies on the relationships between these neonatal AKI indicators and gut microbiota. In order to gain fresh insights into the gut-kidney axis of neonatal AKI, this review is based on the gut-kidney axis and describes relationships between gut microbiota and neonatal AKI biomarkers.
引用
收藏
页码:3529 / 3547
页数:19
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