Preventative and therapeutic potential of animal milk components against COVID-19: A comprehensive review

被引:9
作者
Singh, Parminder [1 ]
Hernandez-Rauda, Roberto [2 ]
Pena-Rodas, Oscar [2 ]
机构
[1] Govt Punjab, Dept Anim Husb Amritsar, Amritsar 143001, India
[2] Univ Doctor Andres Bello, Lab Inocu Alimentos, San Salvador, El Salvador
基金
英国科研创新办公室;
关键词
animal milk; anti-inflammatory; antivirals; COVID-19; immunomodulators; milk components; SIMPLEX-VIRUS TYPE-1; PERFORMANCE LIQUID-CHROMATOGRAPHY; PERIPHERAL-BLOOD LYMPHOCYTES; RESPIRATORY SYNCYTIAL VIRUS; PRO-INFLAMMATORY CYTOKINES; VITRO ANTIVIRAL ACTIVITY; BOVINE LACTOFERRIN; WHEY PROTEINS; IN-VITRO; FATTY-ACIDS;
D O I
10.1002/fsn3.3314
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The global pandemic of COVID-19 is considered one of the most catastrophic events on earth. During the pandemic, food ingredients may play crucial roles in preventing infectious diseases and sustaining people's general health and well-being. Animal milk acts as a super food since it has the capacity to minimize the occurrence of viral infections due to inherent antiviral properties of its ingredients. SARS-CoV-2 virus infection can be prevented by immune-enhancing and antiviral properties of caseins, alpha-lactalbumin, beta-lactoglobulin, mucin, lactoferrin, lysozyme, lactoperoxidase, oligosaccharides, glycosaminoglycans, and glycerol monolaurate. Some of the milk proteins (i.e., lactoferrin) may work synergistically with antiviral medications (e.g., remdesivir), and enhance the effectiveness of treatment in this disease. Cytokine storm during COVID-19 can be managed by casein hydrolyzates, lactoferrin, lysozyme, and lactoperoxidase. Thrombus formation can be prevented by casoplatelins as these can inhibit human platelet aggregation. Milk vitamins (i.e., A, D, E, and B complexes) and minerals (i.e., Ca, P, Mg, Zn, and Se) can have significantly positive effects on boosting the immunity and health status of individuals. In addition, certain vitamins and minerals can also act as antioxidants, anti-inflammatory, and antivirals. Thus, the overall effect of milk might be a result of synergistic antiviral effects and host immunomodulator activities from multiple components. Due to multiple overlapping functions of milk ingredients, they can play vital and synergistic roles in prevention as well as supportive agents during principle therapy of COVID-19.
引用
收藏
页码:2547 / 2579
页数:33
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