Radiation-induced optic neuropathy: a review

被引:6
作者
Carey, Andrew R. [1 ,3 ]
Page, Brandi R. [2 ]
Miller, Neil [1 ]
机构
[1] Johns Hopkins Univ, Wilmer Eye Inst, Sch Med, Ophthalmol, Baltimore, MD USA
[2] Johns Hopkins Univ, Sch Med, Dept Radiat Oncol, Baltimore, MD USA
[3] Johns Hopkins Wilmer Eye Inst, Ophthalmol, Baltimore, MD 21287 USA
关键词
Optic Nerve; Imaging; Diagnostic tests; Investigation; Drugs; Degeneration; WHOLE-BRAIN RADIOTHERAPY; INTRAVITREAL BEVACIZUMAB; HYPERBARIC-OXYGEN; STEREOTACTIC RADIOSURGERY; PLAQUE RADIOTHERAPY; VISUAL RECOVERY; SKULL BASE; PROTON; NECROSIS; THERAPY;
D O I
10.1136/bjo-2022-322854
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Radiation is a commonly used treatment modality for head and neck as well as CNS tumours, both benign and malignant. As newer oncology treatments such as immunotherapies allow for longer survival, complications from radiation therapy are becoming more common. Radiation-induced optic neuropathy is a feared complication due to rapid onset and potential for severe and bilateral vision loss. Careful monitoring of high-risk patients and early recognition are crucial for initiating treatment to prevent severe vision loss due to a narrow therapeutic window. This review discusses presentation, aetiology, recent advances in diagnosis using innovative MRI techniques and best practice treatment options based on the most recent evidence-based medicine.
引用
收藏
页码:743 / 749
页数:7
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