Electrochemical Phenyl-Carbonyl Coupling Reaction of Aromatic Aldehydes or Ketones

被引:2
作者
Zhang, Zenghui [1 ]
Wang, Haiyang [1 ,2 ]
Zheng, Jinhua [3 ]
Yu, Xiao [1 ]
Liu, Fusheng [2 ]
Zhao, Jinbo [1 ]
Liu, Yi [1 ]
Zhang, Mei [1 ]
Xia, Chengcai [1 ]
Cao, Juan [1 ]
机构
[1] Shandong First Med Univ & Shandong Acad Med Sci, Pharm Coll, Inst Pharmacol, Jinan 271016, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Chem Engn, State Key Lab Base Ecochem Engn, Qingdao 266042, Peoples R China
[3] Taian Ctr Dis Control & Prevent, Tai An 271000, Peoples R China
关键词
LITHIUM PENTAMETHYLCYCLOPENTADIENIDE; NUCLEOPHILIC-ADDITION; ORGANIC-SYNTHESIS; BOND-CLEAVAGE;
D O I
10.1021/acs.joc.3c01677
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An electrochemical phenyl-carbonyl coupling reaction of aromatic aldehydes or ketones to synthesize 4-(hydroxy-(phenyl)-methyl)-benzaldehyde derivatives has been developed. The method shows high chemoselectivity, broad functional group compatibility, atom economy, and environmental benignity and has good potential applicability.
引用
收藏
页码:15687 / 15695
页数:9
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