Dairy bioactives and functional ingredients with skin health benefits

被引：8
作者：
Augustyniak, Aleksandra [1 ,4 ]
Gottardi, Davide [2 ]
Giordani, Barbara [3 ]
Gaffey, James [1 ]
Mahon, Helena Mc [1 ]
机构：
[1] Munster Technol Univ Kerry, Tralee, Kerry, Ireland
[2] Univ Bologna, Dept Agr & Food Sci, Piazza Goidanich 60, Cesena, Italy
[3] Univ Bologna, Dept Pharm & Biotechnol, Via S Donato 19-2, Bologna, Italy
[4] Munster Technol Univ Kerry, Tralee, Kerry, Ireland
来源：
JOURNAL OF FUNCTIONAL FOODS | 2023年 / 104卷
基金：
欧盟地平线“2020”;
关键词：
Cheese whey; Skin; Extracellular matrix molecules; Antioxidant; TEER; Sustainability; WHEY-PROTEIN SUPPLEMENTATION; TGF-BETA; MESSENGER-RNA; GROWTH-FACTOR; CHEESE WHEY; COLLAGEN PRODUCTION; GLUTATHIONE LEVELS; EPIDERMAL FUNCTION; ELASTIN SYNTHESIS; DOUBLE-BLIND;
D O I：
10.1016/j.jff.2023.105528
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The potential of whey from Italian cheese productions to support skin health and anti-ageing mechanism was studied. The effect of whey on dermal and epidermal cells was evaluated. Whey inhibited the activity of elastase and tyrosinase enzymes by 60% and 32%, respectively. Whey cytotoxicity against tested skin cell lines, human fibroblasts (HDFa) and keratinocytes (HaCaT) was not observed. Moreover, the antioxidant activity of the samples was noted, after treatment with whey intracellular ROS level was decreased by 87% in comparison with the hydrogen peroxide-treated cells. Fibroblasts produced a significant amount of extracellular matrix molecules, collagen I, elastin and glycosaminoglycans as a result of treatment with tested whey. In addition, the ability of samples to improve the cell barrier integrity of keratinocytes was proven. The obtained results indicate that pure whey supports skin health and shows potential to be used by the cosmetic industry.
引用
收藏
页数：11
相关论文
共 104 条
[1]   Comparison of bioethanol and beta-galactosidase production by Kluyveromyces and Saccharomyces strains grown in cheese whey [J].
Alves, Erika de Padua ;
Ito Morioka, Luiz Rodrigo ;
Suguimoto, Helio Hiroshi .
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 2019, 72 (03) :409-415
[2]   Whey Protein Versus Whey Protein Hydrolyzate for the Protection of Azoxymethane and Dextran Sodium Sulfate Induced Colonic Tumors in Rats [J].
Attaallah, Wafi ;
Yilmaz, Ayse Mine ;
Erdogan, Nusret ;
Yalcin, A. Suha ;
Aktan, A. Ozdemir .
PATHOLOGY & ONCOLOGY RESEARCH, 2012, 18 (04) :817-822
[3]   Inhibitory activity against plasmin, trypsin, and elastase in rennet whey and in cheese fortified with whey protein [J].
Benfeldt, C ;
Sorensen, J ;
Petersen, TE .
JOURNAL OF DAIRY SCIENCE, 1998, 81 (03) :615-620
[4]   Harnessing the nutritional potential of concentrated whey for enhanced galactose flux in fermentative yeast [J].
Beniwal, Arun ;
Saini, Priyanka ;
De, Sachinandan ;
Vij, Shilpa .
LWT-FOOD SCIENCE AND TECHNOLOGY, 2021, 141
[5]  
Blazic M., 2018, Croatian Journal of Food Science and Technology, V10, P255, DOI [10.17508/cjfst.2018.10.2.09, 10.17508/cjfst.2018.10.2.09, 10.17508/CJFST.2018.10.2.09]
[6]   Recent advances in whey processing and valorisation: Technological and environmental perspectives [J].
Buchanan, Dominic ;
Martindale, Wayne ;
Romeih, Ehab ;
Hebishy, Essam .
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 2023, 76 (02) :291-312
[7]   Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial [J].
Bumrungpert, Akkarach ;
Pavadhgul, Patcharanee ;
Nunthanawanich, Pornpimon ;
Sirikanchanarod, Anchalee ;
Adulbhan, Araya .
JOURNAL OF MEDICINAL FOOD, 2018, 21 (06) :612-616
[8]   Poly(3-hydroxybutyrate) bioproduction in a two-step sequential process using wastewater [J].
Carlozzi, Pietro ;
Giovannelli, Alessio ;
Traversi, Maria Laura ;
Touloupakis, Eleftherios .
JOURNAL OF WATER PROCESS ENGINEERING, 2021, 39
[9]   Lactic acid production using cheese whey based medium in a stirred tank reactor by a ccpA mutant of Lacticaseibacillus casei [J].
Catone, Mariela Veronica ;
Palomino, Maria Mercedes ;
Legisa, Danilo Mario ;
Fina Martin, Joaquina ;
Monedero Garcia, Vicente ;
Ruzal, Sandra Monica ;
Allievi, Mariana Claudia .
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2021, 37 (04)
[10]   Effect of Seasonality on Microbiological Variability of Raw Cow Milk from Apulian Dairy Farms in Italy [J].
Celano, Giuseppe ;
Calasso, Maria ;
Costantino, Giuseppe ;
Vacca, Mirco ;
Ressa, Arianna ;
Nikoloudaki, Olga ;
De Palo, Pasquale ;
Calabrese, Francesco Maria ;
Gobbetti, Marco ;
De Angelis, Maria .
MICROBIOLOGY SPECTRUM, 2022, 10 (05)
12345678910