Thoracic epidural Ewing sarcoma mimicking an epidural abscess: A case report

被引:2
作者
Lath, Nikhil [1 ]
Joshi, Padam Raj [1 ]
Kumari, Khusbu [1 ,3 ]
Neupane, Sandeep [1 ]
Ranjan, Ritika [1 ]
Ghimire, Nischal [2 ]
机构
[1] Maharajgunj Med Campus, Kathmandu 44600, Nepal
[2] Tribhuvan Univ Teaching Hosp, Dept Orthoped, Kathmandu 44600, Nepal
[3] Tribhuvan Univ Teaching Hosp, Inst Med, Maharajgunj Med Campus, Kathmandu 44600, Nepal
来源
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS | 2023年 / 107卷
关键词
Case report; Extra osseous; Ewing sarcoma; Epidural abscess; TUMORS;
D O I
10.1016/j.ijscr.2023.108297
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction and importance: Ewing's sarcoma (ES) is a malignant mesenchymal tumor that is categorized as a primitive neuroectodermal tumor (PNET) and is a member of the "small round-cell tumor" family. Spinal extraosseous extradural lesions are highly uncommon in PNETs. There are few clinical studies and information on extra-osseous Ewing tumor outcomes. Case presentation: A 19-year-old woman, with progressive dull aching low back pain of a duration of one month presented. Examination revealed, no knee or ankle reflexes and an MRC power of 0/5 across bilateral ankle and knee joints. The bilateral lower limb's pain, touch, and temperature all received a score of 0/2 on the sensory grading scale. An x-ray revealed radio-opacity at the 9th and 10th thoracic vertebra. The diagnosis of Pott's spine having a likely tubercular abscess was made after an MRI revealed a heterogeneously enhancing collection at T9 -T10 communicating with the posterior epidural space. During surgery, an isolated epidural mass with no apparent bony extension was present. The diagnosis was changed to EES based on the results of the histopa-thology and CD 99 immunohistochemistry tests. Chemotherapy was started. Following up with the patient two months later revealed that her power and sensation in both lower limbs had improved. Clinical discussion: Usually, children and young adults are affected by Ewing's sarcoma. Due to the rarity of extradural thoracic Ewing sarcoma, its exact prevalence is unknown, Most EES have early distant metastases to the lungs and bones and are rapidly growing. It exhibits the compressive myelopathy symptom. It is challenging to distinguish EES from other spinal tumors and from the TB spine because no specific radiologic patterns for intra-spinal EES and PNETs have been described. Due to its rarity, the spinal epidural treatment protocol is not well established. However, the reported cases show that excision and combined radiotherapy have promising outcome. Conclusion: Epidural Ewing sarcoma should be one of the differentials even in the region with a high prevalence of Potts's spine in young patients presenting with back pain and myelopathy-like symptoms. Ewing sarcoma treatment plans are subject to significant, even month-to-month, changes.
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共 14 条
  • [1] The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines
    Agha, Riaz A.
    Borrelli, Mimi R.
    Farwana, Reem
    Koshy, Kiron
    Fowler, Alexander J.
    Orgill, Dennis P.
    Zhu, Hongyi
    Alsawadi, Abdulrahman
    Noureldin, Ashraf
    Rao, Ashwini
    Enam, Ather
    Thoma, Achilleas
    Bashashati, Mohammad
    Vasudevan, Baskaran
    Beamish, Andrew
    Challacombe, Ben
    De Wilde, Rudy Leon
    Machado-Aranda, David
    Laskin, Daniel
    Muzumdar, Dattatraya
    D'cruz, Anil
    Manning, Todd
    Healy, Donagh
    Pagano, Duilio
    Goel, Prabudh
    Ranganathan, Priya
    Pai, Prathamesh S.
    Raja, Shahzad
    Athe, M. Hammad
    Kadioazlu, Huseyin
    Nixon, Iain
    Mukherjee, Indraneil
    Gomez Riva, Juan
    Raveendran, Kandiah
    Derbyshire, Laura
    Valmasoni, Michele
    Chalkoo, Mushtaq
    Raison, Nicholas
    Muensterer, Oliver
    Bradley, Patrick
    Roberto, Coppola
    Afifi, Raafat
    Rosin, David
    Klappenbach, Roberto
    Wynn, Rolf
    Giordano, Salvatore
    Basu, Somprakas
    Surani, Salim
    Suman, Paritosh
    Thorat, Mangesh
    [J]. INTERNATIONAL JOURNAL OF SURGERY, 2018, 60 : 132 - 136
  • [2] Prognostic factors and clinical outcome of patients with Ewing's sarcoma family of tumors in adults: multicentric study of the Anatolian Society of Medical Oncology
    Arpaci, Erkan
    Yetisyigit, Tarkan
    Seker, Metin
    Uncu, Dogan
    Uyeturk, Ummugul
    Oksuzoglu, Berna
    Demirci, Umut
    Coskun, Ugur
    Kucukoner, Mehmet
    Isikdogan, Abdurrahman
    Inanc, Mevlude
    Alkis, Necati
    Ozkan, Metin
    [J]. MEDICAL ONCOLOGY, 2013, 30 (01)
  • [3] Ewing's sarcoma
    Balamuth, Naomi J.
    Womer, Richard B.
    [J]. LANCET ONCOLOGY, 2010, 11 (02) : 184 - 192
  • [4] Ben Kridis W, 2017, REV RECENT CLIN TRIA, V12, P19, DOI 10.2174/1574887112666170120100147
  • [5] Ewing's sarcoma family of tumors: Current management
    Bernstein, Mark
    Kovar, Heinrich
    Paulussen, Michael
    Randall, R. Lor
    Schuck, Andreas
    Teot, Lisa A.
    Juergens, Herbert
    [J]. ONCOLOGIST, 2006, 11 (05) : 503 - 519
  • [6] de Alava Enrique, 2017, Surg Pathol Clin, V10, P575, DOI 10.1016/j.path.2017.04.001
  • [7] Dogan Seref, 2009, Spine J, V9, pe9, DOI 10.1016/j.spinee.2007.11.003
  • [8] Clinical presentation, histology, and treatment in 430 patients with primary tumors of the spinal cord, spinal meninges, or cauda equina Clinical article
    Engelhard, Herbert H.
    Villano, J. Lee
    Porter, Kimberly R.
    Stewart, Andrew K.
    Barua, Manali
    Barker, Fred G., II
    Newton, Herbert B.
    [J]. JOURNAL OF NEUROSURGERY-SPINE, 2010, 13 (01) : 67 - 77
  • [9] Spinal tuberculosis: A review
    Garg, Ravindra Kumar
    Somvanshi, Dilip Singh
    [J]. JOURNAL OF SPINAL CORD MEDICINE, 2011, 34 (05) : 440 - 454
  • [10] Diagnosis and treatment of Ewing's sarcoma
    Iwamoto, Yukihide
    [J]. JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2007, 37 (02) : 79 - 89