Coronary artery bypass grafting in left ventricular dysfunction: when and how

被引:4
作者
Iacona, Gabriele M. [1 ]
Bakhos, Jules J. [1 ]
Tong, Michael Z. [1 ]
Bakaeen, Faisal G. [1 ,2 ]
机构
[1] Cleveland Clin, Heart Vasc & Thorac Inst, Coronary Ctr, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44195 USA
[2] Cleveland Clin, Heart Vasc & Thorac Inst, Dept Thorac & Cardiovasc Surg, Desk J4-1,9500 Euclid Ave, Cleveland Hts, OH 44195 USA
关键词
cardioplegia; coronary artery bypass grafting; heart failure; low ejection fraction; off-pump coronary artery bypass grafting; LONG-TERM OUTCOMES; CARDIAC-SURGERY; EJECTION FRACTION; RANDOMIZED-TRIAL; OFF-PUMP; LEVOSIMENDAN; HEART; CARDIOPLEGIA; PROTECTION; SURVIVAL;
D O I
10.1097/HCO.0000000000001090
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review The surgical management of patients undergoing coronary artery bypass grafting (CABG) with low ejection fraction presents unique challenges that require meticulous attention to details and good surgical technique and judgement. This review details the latest evidence and best practices in the care of such patients.Recent findings CABG in patients with low ejection fraction carries a significant risk of perioperative mortality and morbidity related to the development of postcardiotomy shock. Preoperative optimization with pharmacological or mechanical support is required, especially in patients with cardiogenic shock. Rapid and complete revascularization is what CABG surgeons aim to achieve. Multiple arterial revascularization should be reserved to selected patients. Off-pump CABG, on-pump breathing heart CABG, and new cardioplegic solutions remain of uncertain benefit compared with traditional CABG.Summary Tremendous advancements in CABG allowed surgeons to offer revascularization to patients with severe left ventricular dysfunction and multivessel disease with acceptable risk. Despite that, there is a lack of comprehensive and robust studies particularly on long-term outcomes. Individualized patient assessment and a heart team approach should be used to determine the optimal surgical strategy for each patient.
引用
收藏
页码:464 / 470
页数:7
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