GINA Implementation Improves Asthma Symptoms Control and Lung Function: A Five-Year Real-World Follow-Up Study

被引:1
作者
Tho, Nguyen Van [1 ,2 ]
Quan, Vu Tran Thien [2 ,3 ]
Dung, Do Van [4 ]
Phu, Nguyen Hoang [5 ]
Dinh-Xuan, Anh Tuan [6 ]
Lan, Le Thi Tuyet [2 ]
机构
[1] Univ Med & Pharm Ho Chi Minh City, Fac Med, Dept TB & Lung Dis, Ho Chi Minh City, Vietnam
[2] Univ Med & Pharm Ho Chi Minh City, Univ Med Ctr, Dept Pulm Funct Explorat, Ho Chi Minh City, Vietnam
[3] Univ Med & Pharm Ho Chi Minh City, Fac Med, Dept Pathophysiol Immunol, Ho Chi Minh City, Vietnam
[4] Univ Med & Pharm Ho Chi Minh City, Fac Publ Hlth, Dept Biostat, Ho Chi Minh City, Vietnam
[5] Dong Nai Gen Hosp, Dept Pulmonol, Bien Hoa City, Vietnam
[6] Hop Cochin, AP HP, Serv Physiol Explorat Fonct, Paris, France
来源
JOURNAL OF PERSONALIZED MEDICINE | 2023年 / 13卷 / 05期
关键词
asthma; GINA; lung function; pulmonary function tests; spirometry; ADHERENCE; ADULTS; OBSTRUCTION; RISK;
D O I
10.3390/jpm13050809
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Symptoms control remains challenging for most patients with asthma. This study was conducted to evaluate the level of asthma symptoms control and lung function over 5 years of GINA (Global INitiative for Asthma) implementation. We included all patients with asthma who had been managed following GINA recommendations at the Asthma and COPD Outpatient Care Unit (ACOCU) of the University Medical Center in Ho Chi Minh City, Vietnam from October 2006 to October 2016. Of 1388 patients with asthma managed following GINA recommendations, the proportion of patients with well-controlled asthma significantly improved from 2.6% at baseline to 66.8% at month 3, 64.8% at year 1, 59.6% at year 2, 58.6% at year 3, 57.7% at year 4, and 59.5% at year 5 (p < 0.0001 for all comparisons). The proportion of patients with persistent airflow limitation significantly decreased from 26.7% at baseline to 12.6% at year 1 (p < 0.0001), 14.4% at year 2 (p < 0.0001), 15.9% at year 3 (p = 0.0006), 12.7% at year 4 (p = 0.0047), and 12.2% at year 5 (p = 0.0011). In patients with asthma managed according to GINA recommendations, asthma symptoms control and lung function improved after 3 months and the improvement was sustained over 5 years.
引用
收藏
页数:11
相关论文
共 35 条
  • [1] Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma
    Aaron, Shawn D.
    Vandemheen, Katherine L.
    FitzGerald, J. Mark
    Ainslie, Martha
    Gupta, Samir
    Lemiere, Catherine
    Field, Stephen K.
    McIvor, R. Andrew
    Hernandez, Paul
    Mayers, Irvin
    Mulpuru, Sunita
    Alvarez, Gonzalo G.
    Pakhale, Smita
    Mallick, Ranjeeta
    Boulet, Louis-Philippe
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (03): : 269 - 279
  • [2] [Anonymous], 2006, GLOB STRAT ASTHM MAN
  • [3] [Anonymous], 1995, Global Strategy for Asthma Management and Prevention
  • [4] Asthma and Adherence to Inhaled Corticosteroids: Current Status and Future Perspectives
    Barnes, Camilla Bosley
    Ulrik, Charlotte Suppli
    [J]. RESPIRATORY CARE, 2015, 60 (03) : 455 - 468
  • [5] Can guideline-defined asthma control be achieved? The gaining optimal asthma control study
    Bateman, ED
    Boushey, HA
    Bousquet, J
    Busse, WW
    Clark, TJH
    Pauwels, RA
    Pedersen, SE
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 170 (08) : 836 - 844
  • [6] Global Initiative for Asthma 2016-derived asthma control with fluticasone propionate and salmeterol A Gaining Optimal Asthma Control (GOAL) study reanalysis
    Bateman, Eric D.
    Busse, William
    Pedersen, Soren E.
    Bousquet, Jean
    Huang, Shaoguang
    Zhou, Xin
    Gul, Nadeem
    Hollis, Sally
    Gibbs, Michael
    [J]. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2019, 123 (01) : 57 - +
  • [7] Treatment adherence in asthmatic patients: The last frontier?
    Bateman, Eric D.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (06) : 1269 - 1270
  • [8] Inhaled Corticosteroid Therapy in Adult Asthma Time for a New Therapeutic Dose Terminology
    Beasley, Richard
    Harper, James
    Bird, Grace
    Maijers, Ingrid
    Weatherall, Mark
    Pavord, Ian D.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199 (12) : 1471 - 1477
  • [9] Asthma prescribing: Where are we headed?
    Beasley, Richard
    Hardy, Jo
    Hancox, Robert
    [J]. RESPIROLOGY, 2017, 22 (08) : 1487 - 1488
  • [10] Adherence and persistence with fluticasone propionate/salmeterol combination therapy
    Bender, Bruce G.
    Pedan, Alex
    Varasteh, Laleh T.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 118 (04) : 899 - 904